摘要
目的 探讨玻璃体视网膜手术后糖皮质激素性高眼压的临床特点及危险因素。方法 回顾性分析2002年5月至2005年5月期间来我院眼科玻璃体视网膜手术患者使用糖皮质激素类药物情况及眼压情况。结果 866例全部使用糖皮质激素，其中126例发生糖皮质激素性高眼压，男性89例，女性37例；年龄9～70岁，平均（38．90±15．57）岁。年轻男性、复杂的玻璃体手术、住院天数、全身和局部使用激素时间、白内障为玻璃体视网膜术后糖皮质激素性高眼压的危险因素。合并近视、高血压、糖尿病等疾病的比例与未发生糖皮质激素性高眼压病例无统计学差异。结论 玻璃体视网膜手术患者糖皮质激素性高眼压的发生率为14．55％。眼局部长期大量使用激素是其发生的重要危险因素。
Objective To investigate the clinical characteristic and risk factors of corticosteriod-induced ocular hypertension after vitreoretinal surgery. Methods Retrospective analysis was made based on the clinical data of 866 patients, including 126 corticosteriod-induced ocular hypertension （89 male, 37 female, age range 9 - 70 years old） after vitreoretinal surgery during May 2002 to May 2005. Results All cases used glucocorticoid locally or systemically. Multi-variance logistic analysis showed that male, complicated vitreoretinal surgery, longer hospital stay, therapeutic duration with glucocorticoid, cataracta were the independent predictive factors, while myopia, hypertension, diabetes were not closely related to corticosteroid-induced ocular hypertension. Conclusion The incidence of corticosteriod-induced ocular hypertension after vitreoretinal surgery was 14.55%. The important factor leading to ocular hypertension is long-term application of glucocorticoid.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
2006年第12期1339-1341,共3页
Journal of Third Military Medical University
