摘要
目的 评价华法林用于心房颤动病人抗凝治疗的合适剂量和安全性。方法95例房颤病人随机分为2组，用不同剂量华法林治疗：治疗组45例，INR2．0-2．5；对照组50例，INR：1．5-2．0。结果治疗组与对照组比较，脑栓塞的发生率无显著性差异，脑出血、大出血、死亡事件的发生率也．无显著性差异。结论INR保持在1．5-2．0之间的低剂量华法林在房颤病人中的使用是安全有效的。
Objective To assess the ideal dosage and security of warfarin in treatment of antieoagulation in patients with atrial fibrillation. Methods 95 patients with atrial fibrillation were derided into two groups and treated by different doses of warfarin in order to keep INR at certain range： group Ⅰ included 45 patients kept INR at 2.0 - 2.5 and group Ⅱ included 50 patients kept INR at 1.5 - 2.0. Results There was no significant difference in the incidence of brain thromboembolism, brain hemorrhage, fatal hemorrhage and death event between two groups. Conclusions It is safe and effective for patients with atrial fibrillation to take low dosage warfarin with INR keeping 1.5 - 2.0.
出处
《心脑血管病防治》
2006年第3期153-154,共2页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词
心房颤动
华法林
安全性
Atrial fibrillation
Warfarin
Anticoagulation
Security
