摘要
目的观察益气活血解毒方药对小鼠Lewis肺癌癌细胞Mg2+-ATP酶、葡萄糖-6-磷酸酶(G-6-P酶)活性的影响。方法应用酶细胞化学染色法观察Lewis肺癌细胞酶活性的改变。结果质膜标志酶Mg2+-ATPase、内质网标志酶G-6-Pase反应颗粒变小,数量减少,密度减低,提示酶活性明显下降。结论益气活血解毒方药降低肺癌细胞质膜标志酶Mg2+-ATPase及内质网标志酶G-6-Pase活性。
Objective To observe the effect of Yiqihuoxuejiedu formula on the activity of G-6-Pase and Mg^2＋-ATPase of Lewis cells of mice with Lewis lung cancer. Method Enzyme cytochemistry was used to detect the activity of G-6-Pase and Mg^2＋-ATPase of the mice lung cancer of Lewis cells. Result The response granules of G-6-Pase and Mg^2＋-ATPase in the mice lung cancer of Lewis cells became smaller after the treatment of the Yiqihuoxuejiedu formula, the amount of the granules became fewer, the density was lower, which indicated the activity of enzyme reduced evidently. Conclusion Yiqihuoxuejiedu formula can decrease the activity of the G-6-Pase and Mg^2＋-ATPase.
出处
《中国中医药信息杂志》
CAS
CSCD
2006年第6期37-38,共2页
Chinese Journal of Information on Traditional Chinese Medicine
基金
辽宁省教育厅资助课题(99152133)
