摘要
研究了微波辐射催化合成标题化合物的方法。最优合成条件:催化剂氨基磺酸0.8g,微波功率240W,辐射时间4min,n4-氯苯甲醛∶n乙酰乙酸乙酯∶n尿素为1.0∶1.2∶1.5,在此条件下产率达94.2%。
The synthesis of 4-（4-chlorophenyl）-6-methyl-5-ethoxycarbonyl-3, 4-dihydropyrimidin-2（1H）-one under microwave irradiation was studied. The optimum conditions were as follows： the amount of sulfamic acid was 0.8g; the power of microwave was 240W; the time of irradiation was 4min; n （4-chlorobenzaldehyde） ： n （ethyl acetoacetate） ： n （urea 0.03mol） was 1.0：1.2：1.5. The yield was 94.2%.
出处
《化学试剂》
CAS
CSCD
北大核心
2006年第4期249-251,共3页
Chemical Reagents
