摘要
以3-甲基-5-吡唑啉酮为原料,合成了标题化合物,并对目标物及文献中未见报道的中间体如3-甲基-5-氧代-4-吡唑啉酮腙衍生物等,通过元素分析I、R1、HNMR和质谱分析确定了其结构。
Bromination of 3-methyl-5-pyrazolone （1） in glacial acetic acid gave 3-methyl-4,4-dibromo-5-pyrazolone （2）. 2 Reacted with a series of substituted hydrazines in hot ethanol to afford 3-methy-5-oxo-4-substituted-hydrazono-pyrazole derivatives （3a～3d）. 7-methyl-3-hydroxypyrazolo [4,3-e]-1,3,4-oxadiazine （6） was formed by cyclizafion of 4-ethoxycarbonylhydrazone derivative 3a in 2% NaOMe solution.
出处
《化学试剂》
CAS
CSCD
北大核心
2006年第4期235-236,251,共3页
Chemical Reagents
