摘要
目的：观察１，６－二磷酸果糖（ＦＤＰ）治疗重型脑梗死的疗效。方法：重型脑梗死３２例（男性２１例，女性１１例，年龄５９±ｓ１２３），在常规药物治疗的同时加用１，６－二磷酸果糖５ｇ，溶于注射用水５０ｍＬ中静脉滴注，ｂｉｄ～ｑｉｄ，连用５～７ｄ；并与对照组３２例（男性１８例，女性１４例，年龄５８±１１ａ）进行比较。结果：对照组和ＦＤＰ组的显效率分别是５６％和８１％，总有效率分别是７２％和９４％。结论：ＦＤＰ组疗效明显优于对照组（Ｐ＜０．０５），无毒副作用，说明该药对脑梗死急性期有应用价值。
AIM: To observe the efficacy of fructose 1, 6-diphosphate (FDP) in the treatment of severe cerebral infarction. METHODS: Thirty-two patients with severe cerebral infarction (M 21, F 11, age 59±s 12 a) were given FDP 5 g in distilled water 50 mL iv, gtt, bid-qid for 5-7 d in addition to conventional therapy. The other similar thirty-two patients (M 18, F14,age 58±11 a) received conventional therapy (20% mannitol 250 mL iv,q6-8h for 10-15d, citicoline, piracetam). RESULTS: Results showed that the total response rate was 94% in the former group and 72% in the latter group (P<0.05) . CONCLUSION: We think that FDP may be a valuable drug in treating acute cerebral infarction.
出处
《新药与临床》
CSCD
北大核心
1996年第2期69-71,共3页
关键词
重型
脑梗塞
治疗
二磷酸果糖
hexosedihosphates
cerebral infaraction
anoxia
fructose 1,6-diphosphate
