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不孕不育患者的抗精子抗体分析 被引量:9

Analysis of antisperm antibody in patients with infertility.
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摘要 目的分析抗精子抗体(AsAb)与不孕不育的关系。方法采用ELISA方法检测1086例不孕不育症患者血清中的抗精子抗体(总抗)。结果1086例患者血清中,AsAb阳性313例,占28.82%,其中男性阳性率为24.16%(115/476),女性阳性率为32.46%(198/610),男女之间差异极显著(P<0.01)。结论进行抗精子抗体检测对不孕症的诊断和治疗具有重要意义。 Objective: To analyze the relationship between the patients with Infertility and antisperm antibody (AsAb). Methods: Applying enzyme linked immunsorbent assay (ELISA) to measure level of total antibody (TIg) of AsAb in 1086 examples serum of patients with Infertility. Results: 313 out of 1086 serum samples from these infertile patients showed positive reaction of AsAb, with an incidence of 28.82%. The serum positive rate in male patients was 24. 16% (115/476) : whereas that in female patients was 32.46% (198/610), the positive rate of AsAb in female patients was higher than that of male patients ( P 〈 0. 01 ). Conclusion: The detection of the AsAb will provide the evidence for the diagnosis and cure of infertility.
出处 《中国优生与遗传杂志》 2006年第6期110-110,118,共2页 Chinese Journal of Birth Health & Heredity
关键词 AsAb 不孕 不育 ELISA 抗精子抗体 Antisperm antibody Infertility ELISA
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  • 1罗自强,生物医学工程学报,1990年,7卷,3期,179页
  • 2温健萍,生物医学工程学报,1989年,6卷,2期,119页
  • 3团体著者,人类精液及精子宫颈粘液相互作用实验室检验手册(第3版),1994年,3,30页
  • 4郭祖超,医用数理统计方法(第3版),1988年,573页

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