摘要
目的:探讨新型隐球菌脑膜炎(CNM)的临床特点及诊断方法。方法:对18例CNM患者的临床资料进行回顾性分析并文献复习。结果:18例患者均经病原学确诊。大部分CNM患者为亚急性起病,临床表现无特异性,误诊率高,首诊误诊率为72%,其中误诊为结核性脑膜炎的占69%。结论:脑脊液中找到新型隐球菌是诊断该病的重要依据,多种快速检测手段结合可提高早期诊断率。
objective: To explore tile clinical characters and diagnosis of cryptococcus neoformans meningitis(CNM). Methods: We retrospectively analysed the clinical data of 18 patients with cryptococcal meningitis. The revelant medical literature was reviewed, Results: All patients were identified by pathogen. Most showed suhacute clinical course. Clinical presentations of CNM were not special, so it was easily misdiagnosised. Misdiagnosis rate was 72% at first time to consult a doctor. The cases misdiagnosised with tubercular encephmneningitis accounted for 69%. Conclusions: diagnosis is dependent on the finding of Cryptococcus neoformans. Rapid methods should he united to improve early diagnosis.
出处
《脑与神经疾病杂志》
2006年第3期180-182,共3页
Journal of Brain and Nervous Diseases
关键词
新型隐球菌
脑膜炎
检测
诊断
Cryptococcus neoformans meningitis detection diagnosis