摘要
目的:研究小儿反复呼吸道感染(RRTI)的中医证候分布规律。方法:在文献系统回顾基础上设计临床调查问卷,通过较大样本的临床流行病学前瞻性调查研究,采集症状、体征、舌象、脉象等基本信息,以聚类分析、频数统计、因子分析、方差分析、χ2检验等方法,归纳南北两地RRTI的中医证候分布规律。结果:对南北两地1 274名适龄儿童的临床调查显示,急性感染期南方分为气虚外感、风邪犯肺证,寒热错杂证,热重于寒、阴虚外感证,外感风寒证;北方分为外感风寒证、外感风热证、气虚外感证。临床缓解期南方分为脾肺气虚夹阴虚证、胃火炽盛肝胃不和夹阴虚证、肝郁脾虚夹阴虚证、脾肾阳虚夹气虚证;北方分为阴虚夹脾气虚证、肺脾气虚证、脾肾阳虚夹气滞证,尚有部分近似健康儿童。小儿RRTI的社区发病率为8.8%,性别间无显著性差异;年龄越小发病率越高。结论:在RRTI中医证候分布规律领域存在较大研究空间,较大样本的临床流行病学调查为之提供了科学依据。南北两地的中医证候分布规律的提出可作为临床诊断、预防、治疗的指导。
Objectives： To investigate distribution rules of TCM syndrome by studying children＇s recurrent respiratory tract infections（RRTI） . Methods： Create the clinical questionnaire based on symptoms, signs, tongue and pulse manifestations,etc. ,thus perform an investigation of large sample to study the syndrome distribution rules of RRTI by means of cluster analysis, frequency statistics, factor analysis, ANOVA,Chisquare test. Results：1 274 cases of RRTI were investigated. The study indicated that syndrome distribution rules in south and north China were different. In acute stage there were 4 syndrome types in the south： exterior syndrome due to Qi-deficiency,intermingled cold and heat exterior syndrome with heat in prevalence,exterior syndrome due to Yin-deficiency, wind-cold exterior syndrome. 3 types in the north： wind-cold exterior syndrome,wind-heat exterior syndrome,exterior syndrome due to Qi-deficiency. In chronic stage there were 4 types in the south： Qi-deficiency of lung and spleen with Yin deficiency,disharmony of liver and stomach with stomach heat and Yin-deficiency, disharmony of liver and spleen with Yin-deficiency, spleen and kidney Yang-deficiency with Qi-deficiency. 4 types in the north： Yin-deficiency with spleen Qi deficiency, Qi deficiency of spleen and lung, spleen and kidney Yang deficiency with Qi stagnation, and unsymptomatic children. The average community incidence of RRTI was 8. 8%, decreased with age increasing. Conclusion：There is certain space to study syndrome distribution rules of children＇s RRTI. The clinical epidemiological investigation can provide scientific evidence for the study. The results of syndrome distribution rules of RRTI in north and south may serve as reference for clinical practice.
出处
《山东中医杂志》
2006年第6期369-372,共4页
Shandong Journal of Traditional Chinese Medicine
基金
国家中医药管理局课题(编号04-05-LP23)
