摘要
目的探讨磁场对AM I的保护作用。方法将大鼠随机分为5组即:空白对照组、磁场对照组、AM I组、AM I药物(心得安)治疗组和AM I磁场治疗组。采用虫荧光素酶法及放射免疫技术法对实验性大鼠进行心肌ATP含量、及血浆cAMP、cGMP的测定。结果AM I磁场治疗组心肌ATP明显高于AM I组(P<0.01)与药物治疗组相近似。AM I的血浆cAMP、cGMP含量明显高于空白对照组(P<0.01)及磁场对照组,AM I磁场治疗组与药物治疗组明显低于AM I组(P<0.01)。结论磁场能降低AM I大鼠cAMP、cGMP的含量,增加心肌ATP含量,对心肌具有保护作用,这也为磁场用于AM I的治疗提供了实验依据。
Objective This paper studied protective effect of magnetic field on AMI big rats. Methods The big rats were randomly divided into 5 groups： the blank contrast（ G1 ）, the magnetic field contrast（ G2 ）, AMI group （G3 ）, AMI drug （propranolol） group （ G4 ） and AMI magnetic field （ G5 ）, Results The contents of myocardium ATP were higher than those of G3 （ P 〈 0.01 ）. Plasma cAMP,cGMP of G3 were obviously higher than G1 （ P 〈 0.01 ）, G5 were similar to those of G4. Conclusions The magnetic field has protective effect on experimental AMI myocardium.
出处
《中国地方病防治》
北大核心
2006年第3期144-145,共2页
Chinese Journal of Control of Endemic Diseases
基金
吉林省教育厅资助课题(2003029)
