摘要
１９８４年１０月～１９９３年１０月，我院收治经ＣＴ或ＭＲＩ证实的可供分析的脑转移瘤５４例。临床分析发现：原发肿瘤以肺癌最多，其次为乳腺癌、胃肠道肿瘤、食管癌、鼻咽癌。临床主要表现为颅内压增高、偏瘫、共济失调、癫痫样抽搐等。转移灶部位主要在大脑皮髓质交界处，单发与多发比为１：２。接受放疗、化疗、放化综合治疗、手术治疗的病例数分别为２８、１１、１１、４例，各种治疗的中位生存期分别为５．０、２．５、９．０、７．０月，１年生存率分别为１４．３％、０％、３６．４％、２５％。放疗剂量低于４０Ｇｙ者，预后最差。不论有无颅外肿瘤病灶，放化综合治疗均优于单一治疗。死亡原因分析，脑转移和其它器官转移仍占主要地位。
From October 1984 to October 1993, 54 patients with brain metastatic tumours were treated. Of them, the incidences of the primary tumour were 66. 7% of lung cancer, 14. 8%of breast cancer, 9. 3% of gastro-intesinal tumor, 5. 6% of esophageal cancer, 3. 6% of nasopharyngeal cancer, respectively. Most of the brain metastatic foci were at the boundary zone of the gray white substances. The rate of single focus and multiply foci was 1 vs 2. The number of the patients treated by radiotherapy, radiotherapy combined with chemotherapy,chemotherapy or operation was: 28, 11, 11, 4, respectively. The median survival time of different treatment groups was: 5. 0, 9. 0, 2. 5, 7. 0 months, respectively. The 1-year survival rates were: 14. 3%, 36. 4%, 0%, 25%, respectively. We suggest that the radiation dose shouldn' t be less than 40Gy. The prognosis of the patients with single brain metastatic tumour foci was better than that of the patients with tumor foci out of the brain. Combined radiotherapy with chemotherapy can impove the survival rate and survival quality.
出处
《河南肿瘤学杂志》
1996年第1期37-39,共3页
Henan Journal of Oncology
关键词
脑肿瘤
脑转移癌
综合治疗
放射疗法
药物疗法
brain metastatic tumour
radiotherapy
chemotherapy
combined radiotherapy with chemotherapy
