摘要
目的:观察国产奥扎格雷钠氯化钠注射液治疗急性脑梗塞的疗效及不良反应。方法:95例急性脑梗塞患者随机分为治疗组(奥扎格雷钠组)48例和对照组(尿激酶组)47例,治疗组:奥扎格雷钠氯化钠注射液160mg,静脉滴注,qd×14天,对照组:尿激酶60 000单位+0.9%氯化钠注射液250ml,静脉滴注,qd×7天,分别观察比较治疗效果。结果:治疗组的总有效率为91.67%高于对照组70.21%(P<0.01)。结论:奥扎格雷钠氯化钠注射液治疗急性脑梗死疗效确定,安全、不良反应少。
OBJECTIVE：To observe the efficacy and side - effects of home - made ozagrel sodium chloride （NaCl） injection in the treatment of acute cerebral infarction. METHODS ： 95 cases with acute cerebral infarction were randomly divided into 2 groups ： treatment group （ozagrel group,48 cases） and control group （UK group,47 cases）. Treatment group was given ozagrel NaCl injection 160mg by IV drop, qd for 14 days; Control group was given UK60 000U plus 0.9 % NaCl 250ml by IV drop, qd for 7 days , their therapeutic efficacy and side - effects were compared. RESULTS ： Total effective rate in treatment group was 91.67% ,but that in control group was 70.21% , there was a significant difference between two groups（ P 〈 0.01 ） . CONCLUSION ： Home - made ozagrel NaCl injection has confirmative efficacy on the treatment of acute cerebral infarction , and it is safe and has less side - effects .
出处
《中国医院用药评价与分析》
2006年第2期104-105,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
奥扎格雷钠
急性脑梗塞
临床观察
ozagrel
acute cerebral infarction
clinical observation
