摘要
目的探讨局部亚低温治疗对脑梗死病人血清S-100b蛋白的影响。方法将52例急性脑梗死患者按1∶1配对分为亚低温治疗组(26例)和常规治疗组(26例),ELISA法检测血清S-100b蛋白含量。同时检测26例正常人(对照组)血清S-100b蛋白含量。结果脑梗死病人血清S-100b蛋白含量明显高于对照组(P<0.01);亚低温治疗组病人血清S-100b蛋白含量明显低于非亚低温治疗组,有显著差异(P<0.05)。结论1急性脑梗死病人血清S-100b蛋白水平明显高于正常人,因此S-100b蛋白可作为脑梗死病情观察指标。2局部亚低温治疗能降低脑梗死病人血清S-100b蛋白水平,提示局部亚低温能发挥脑保护作用。
Objective To explore the effect of local mild hypothermia on serum S-100b protein of cerebral infarction patients. Methods 32 cerebral infarction patients were divided into mild hypothermia group and common treatment group. Serum S-100b protein levels were analyzed with ELISA assays. Meanwhile serum S-100bprotein levels were detected in 11 cases regular persons. Results Serum S-100b protein levels in cerebral infarction patients are higher than normal.There are significant differences in the serum S- 100b protein levels between mild hypothermia group and the common treatment group（ P 〈 0.05）. Conclusion local mild hypothermia therapy can decrease the levels of serum S-100b protein in cerebral infarction patients.
出处
《中国实验诊断学》
2006年第5期511-513,共3页
Chinese Journal of Laboratory Diagnosis
