摘要
目的观察卡前列甲酯栓(卡孕栓)对原发性子宫收缩乏力患者产后出血的影响。方法对51例原发性子宫收缩乏力患者胎儿娩出后立即给予卡孕栓1mg舌下含服。50例同期原发性子宫收缩乏力者胎儿娩出后立即臀部肌肉注射缩宫素20单位。观察两组患者的第三产程时间、产后出血量、产后出血发生率等。结果①两组患者年龄、孕周、产次,产时处理,新生儿体重相比差异无显著性(P>0.05),两组有可比性;②卡孕栓组第三产程时间(6.98±3.23)min,产后出血量(298.2±98.2)ml,产后出血发生率5.9%(3/51)。缩宫素组第三产程时间(9.12±3.36)min,产后出血量(298.2±135.3)ml,产后出血发生率28%(14/50),两组相比卡孕栓组第三产程时间、产后出血量及产后出血发生率皆明显少于缩宫素组(P<0.01);③51例服用卡孕栓组患者服药前收缩压(120±15.75)mmHg,舒张压(78±15.75)mmHg,服药后收缩压及舒张压均有所增高,但差异无显著性(P>0.05);④服用卡孕栓组2例出现恶心及呕吐,皆为一过性,无需特殊处理。结论原发性子宫收缩乏力患者胎儿娩出后舌下含服卡孕栓1mg,能产生强有力的子宫收缩,缩短第三产程,减少产后出血,是一种简单、安全、高效的预防产后出血的方法。
Objective To observe the effect of carboprost on postpartum hemorrhage in primary uterine atony. Methods Carboprost 1 mg was given sublingually to the 51 cases of primary uterine atony when the delivery of fetus, The same period 50 cases was given 20U oxycoxin intramuscla when the delivery of fetus. Third stage of labor,the amount of bleeding within 2 hours after the delivery of fetus and the incidence of postpartum hemorrhage were measured, Results ① There was no significant deviation between two groups in age , pregnancy weeks , give birth time ,treatments and neonatal body weight（ P 〉 0.05 ）. ② Carboprost group ：third stage of labor was （6.98 ± 3.23 ） min ,the amount of bleeding after the delivery of fetus was（298.2±98.2）ml ,the incidence of postpartum hemorrha was 5.9%, Oxycoxin group was （9.12±3.36） min, （298.2 ± 135.3 ） ml, 28 %. There was significant deviation between two groups （ P 〈 0.01 ） ;③ C arboprost group systolic pressure was （120 ± 15.75 ） mm Hg, diastolic pressure was（78 ± 15.75 ）mm Hg before oral . There was no significant deviation in systolic pressure and diastolic pressure between before and after oral carboprost ;④ 2 cases had nausea and vomiting. Conclusion Carboprost is more effective in shortening third stage and controlling postpartum hemorrhage. It is simply , salty and high efficency to prevent postpartum hemorrhage.
出处
《临床和实验医学杂志》
2006年第4期378-379,共2页
Journal of Clinical and Experimental Medicine
