小剂量瑞芬太尼在硬膜外麻醉下前列腺电切术中的应用被引量：1

导出

摘要目的观察小剂量瑞芬太尼用于硬膜外麻醉下前列腺电切术的镇痛效应。方法选择前列腺电切术60例,随机分为两组,A组为瑞芬太尼组(n=30),B组为对照组(n=30),两组均选择L2-3行椎管穿刺头向插管硬膜外麻醉,局麻药选用2.0%利多卡因溶液;A组待麻醉效果确切后,微泵输注瑞芬太尼0.07μg/(kg·min),术毕停用瑞芬太尼。观察两组患者术中血流动力学变化,镇静、镇痛效果及不良反应情况。结果两组患者在硬膜外首量后、手术开始置镜时心率、血压比较有显著差异(P<0.01),而瑞芬太尼组心率、血压波动较小。两组的口述描绘四级评分(VDS)比较也有差异(P<0.05)。结论瑞芬太尼微泵静脉输注0.07μg/(kg·min),用于硬膜外麻醉下前列腺电切术镇痛效果良好,能保持患者术中血流动力学的稳定,且能术中唤醒。

作者许春雷

机构地区暨南大学第五附属医院麻醉科

出处《临床和实验医学杂志》 2006年第4期376-377,共2页 Journal of Clinical and Experimental Medicine

关键词小剂量瑞芬太尼硬膜外麻醉前列腺电切术

分类号 R614 [医药卫生—麻醉学]

引文网络
相关文献

参考文献3

1余淑珍,刘保江.瑞芬太尼的药理学、临床研究和应用进展[J].国外医学（麻醉学与复苏分册）,2004,25(6):356-358. 被引量：121
2蒋奕红.两种麻醉方法在前列腺汽化电切术中应用效果的观察[J].中国内镜杂志,2004,10(1):104-104. 被引量：3
3耿志宇,宋琳琳,许幸,吴新民.异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉与静吸复合麻醉的比较[J].中华麻醉学杂志,2004,24(1):14-17. 被引量：318

二级参考文献27

1David S. Hemodynamics and emergence profie of remmifentanil versus fentanyl prospectively compared in a large population of surgical patients. Survey of Anesthesiology,2002,46(4): 207-208.
2Enrique C, Antonio P, Pedro A, et al. A comparison of two constant-dose continuous infusion of remifentanil for severe postoperative pain. Anesthesia & Analgesia, 2001,92(3) :715-719.
3Stefan S, Matthew C, Gavin K. Lack of rapid development of opioid tolerance during alfentanil and remifentanil infusion for postoperative pain. Anesthesia & Analgesia, 1999,89(3): 753.
4Penny KJ, Randall S, James S. The use of remifentanil infusion to allow intraoperative awakening for intentional fracturing of the anterior cervical spine. Anesthesia & Analgesia, 1999,89(4): 1059-1062.
5Danelli G,Berti M, Casati A, et al. Spinal block or total intravenous anaesthesia with propfol and remifentanil for synaecological outpatient procedures. European Journal of Anaesthesiology,2002, 19(8) :594-599.
6Jones R, Pegrum A, Stacey RG. Patient-controlled analgesia using remifentanil in the parturient with thrombocytopaenia. Anaesthesia, 1999,54(5):461-465.
7Victor C, Gilles G, Gilles G, et al. Target-Controlled Infusion for Remifentanil in Vascular Patients Improves Hemodynamics and Decreases Remifentanil Requirement. Anesthesia & Analgesia, 2003,96( 1 ): 33-38.
8Servin F, Desmonts JM, Watkins WD. Remifentanil as an analgesic adjunct in local/regional anesthesia and in monitored anesthesia care. Anesth Analy, 1999,89(4) :28-32.
9Myre K, Raeder J, Rostrup M, et al. Catecholamine release during laparoscopic fundoplication with high and doses of remifentanil. Acta Anaestheiol Scand,2003,47(3): 267-273.
10Barvais L, Engelman E, Eba JM, et al. Effect site concentration of remifentanil and pupofol to noxious stimulation. British Journal of Anaesthesia,2003,91 (3) :347-352.