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化合物wortmannilactones产生菌F01-195的鉴定及发酵条件研究 被引量：2

Identification and study of fermentation condition of wortmannilactones-producing strain F01-195
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摘要 对自云南土壤分离得到的真菌F01-195从形态特征、培养特性等方面进行了分类鉴定,认为该菌株属于邬氏黄丝曲霉(Talaromyceswortmannii),该菌可以产生新的22元环macrolactin类大环内酯类化合物wortmannilactoneA、B、C、D。此外,对该菌株的发酵条件的研究结果表明只有在固体培养条件下该菌株才能产生wortmannilactones。 Fungal strain F01-195 isolated from soil, identified as Talaromyces wortmannii by morphologic and cultural characteristics, can produce new 22-membered triene macrolides wortmannilactone A, B, C and D. Moreover, the fermentation condition of F01-195 was studied. The results showed that wortmannilactones could be only produced on solid medium condition.
作者 刘梅 董悦生 李业英 崔晓兰 石英 林洁 任晓 张华 贺建功
机构地区 华北制药集团新药研究开发中心微生物药物国家工程研究中心
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2006年第5期271-273,305,共4页 Chinese Journal of Antibiotics
基金 基金资助:国家科技部创新药物筛选技术平台研究项目(2002AA2AZ343D)。
关键词 Wortmannilactones 分类鉴定 邬氏黄丝曲霉 Wortmannilactones Classification and identification Talaromyces wortmannii
分类号 Q939.9 [生物学—微生物学]
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参考文献13

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共引文献81

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中国抗生素杂志
2006年 第5期

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