摘要
采用超滤-离子交换色谱法制备的乳铁蛋白的铁结合能力为87.7%,铁饱和度为15.1%。当pH值为7.5,NaHCO3浓度为100mmol/L时,铁结合能力最强。采用低强度的巴氏杀菌可以保持乳铁蛋白的铁结合性能。SD大鼠的动物试验表明,50μg/g·d和250μg/g·d的乳铁蛋白剂量具有显著的升高血红蛋白浓度的作用。乳铁蛋白改善缺铁性贫血的最小有效作用剂量为50μg/g·d。
The iron-binding capacity of lactoferrin was 87.7% produced by ultrafiltration and strong cation exchange chromatography. Its iron saturation point was 15.1%. Lactoferrin exhibited the strongest iron binding capacity at pH7.5 and 100 mmol/L of bicarbonate. In vivo study with SD rats showed that LF could significantly increase the concentration of hemoglobin at doses 50μg/g · d and 250μ g/g · d. The low marginal dose level of LF was 50μ g/g · d.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2006年第5期113-118,共6页
Food Science
关键词
乳铁蛋白
铁结合能力
lactoferrin
iron-binding capacity
