摘要
目的研究福建地区Barrett食管(BE)的发病情况和内镜、临床特点及其与反流性食管炎(RE)的关系。方法根据新标准诊断BE,研究BE患者的内镜下检出率、内镜表现、分型及病理检查结果,分析患者的年龄、性别、症状、幽门螺杆菌(Hp)感染情况及其与RE的关系。结果检出BE为总胃镜检查人数的7.90%,男女之比为1.98,平均年龄(45.1±14.8)岁,仅19.15%有典型反流症状。BE中短节段占81.20%,多为舌状、岛状或包含这2种形状的混合型。食管活检组织病理诊断为肠化型占BE的34.83%,9.88%伴异型增生,胃窦Hp阳性率为39.94%。RE检出率为2.07%,比BE显著降低(P<0.01)。8.42%的BE伴RE,32.11%的RE伴BE。结论福建地区BE患病率较高,多为短节段舌状或岛状,约1/3为肠化型,以中年男性多见,常无症状,与RE无明显相关性,部分伴异型增生。BE的临床意义和预后有待于进一步研究。
Objective To investigate the incidence and clinical and endoscopic characteristics of Barrett＇s esophagus（BE） and the relationship between BE and reflux esophagitis （RE）. Methods Patients with BE were diagnosed according to new standard by endoscopy and histology. The prevalence, form in endoscopy, histology of biopsy, age, sex, symptom, Helicobacter pylori （Hp） infection and relationship between BE and RE were analyzed, Results BE was 7. 90% of the total endoscopy number, and male vs female was 1.98,mean age （45.1± 14.8） years old. Only 19, 15% of BE patients had typical reflux symptoms. 81.20% of BE patients were with short segment BE . Intestinal metaplasia was detected in 34. 83% of BE and dysplasia 9. 88%. 39.94% of BE patients were infected with Hp. Patients with RE （2. 07% ） were significantly less than those of BE（P 〈0. 01 ）. 8.42% of BE patients were also with RE and 32. 11% of RE patients were also with BE. Conclusions The incidence of BE in Fujian of China is high. Most of BE are short segment BE and male and have no typical reflux symptoms. Intestinal metaplasia is found in 1/3 of BE patients. There isn＇t a close association between BE and RE.
出处
《中华内科杂志》
CAS
CSCD
北大核心
2006年第5期393-395,共3页
Chinese Journal of Internal Medicine
基金
福建省青年创新人才项目课题(2002J059)
