摘要
目的探讨成人白血病的危险因素。方法2004年5—12月采用成组设计病例-对照研究,对192例白血病病人和241例社区对照人群进行回顾性调查。调查受试者的一般情况、疾病史、室内外居住环境、有害物质接触史和家族遗传史等,应用非条件Logistic回归模型对资料进行分析。结果多因素Logistic回归分析显示,职业是机关干部(OR=7.06,P<0.01)、住所周围有工厂(OR=5.54,P<0.05)、居室装修后立即入住(OR=4.44,P<0.05)、卧室地面采用释放挥发性有机物(VOCs)的装修材料(OR=3.21,P<0.05)、染发频率大于3.5次/a(OR=1.09,P<0.05)的人群患白血病的危险性较大,均有统计学意义。结论职业、住所周围有工厂、居室装修材料及装修后入住时间短、染发频率大于3.5次/a可能是成人白血病的危险因素。
Objective To explore risk factors for adult leukemia. Methods 192 patients with leukemia and 241 community controls were chosen to carry out a case-control study for finding the indoor environmental factors and the other risk factors for leukemia. The data was statistically analyzed by unconditional logistic： regression. Results It was demonstrated as the risk factors for leukemia that the occupation （OR=7.06, P〈0.01）, housing as soon as the house decoration finished （OR=4.44, P〈0.05）, using the materials containing volatile organic compounds as the bedroom floor （OR=3.21, P〈0.05）, there were factories near the house （OR=5.54, P〈0.05） and the frequency of hair dye using was more than 3.5 times a year （OR=1.09, P〈0.05）. Conclusion The indoor environmental factors investigated in the present paper can be considered as the risk factors for leukemia.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2006年第3期195-197,共3页
Journal of Environment and Health
基金
国家"十五"科技攻关课题基金资助项目(2001BA704B01)
