摘要
目的:了解社区居民对基因检测服务的知晓、需求状况及需求意愿的影响因素。方法:采用典型抽样方法,对杭州市下城区1647户居民进行问卷调查。结果:调查人群对基因检测知晓率为21.8%,需求率为12.7%,有需求意愿的占到61.9%。有无家庭成员患病(OR=1.619,95%CI=1.279-2.049)、对基因检测服务知晓情况(OR=2.368,95%CI=1.782-3.146)、有无家族遗传史(OR=2.784,95%CI=1.685-4.600)年龄(x2=27.210,P<0.001)、对婚前基因检测的认可度(x2=23.185,P<0.001)等五个因素对社区居民基因检测服务需求意愿有显著影响。结论:社区居民对基因检测服务需求意愿较强,但是知晓率、需求率均偏低。有待加强相关方面的宣传、教育、培训等工作。
Objective：To assess the community residents＇ awareness and demand state of gene testing service; and analyze the influence factors to demand awareness. Methods：Typical sampling to select 1647 households in Xiacheng distracts of Hangzhou city for questionnaire. Results：The awareness rate of gene testing is 21.8%, demand rate is 12.7%, and intention rate of demand is 61.9%. The significant influence factors to demand willingness of communities residents are as follows： sicken family members（OR=l.619,95%CI= 1.279-2.049）, awareness ofgene testing（OR=2.368,95%CI=1.782-3.146）,genetic history（OR=2.784,95%CI=1.685-4.600）,age（Х^2 =27. 210,P〈0.001 ）, and the attitude to premarital gene testing （Х^2 = 23.185,P〈0.001）.Conclusion：Communities residents＇ demand willingness of the gene testing service is strong, but the rate of awareness and demand rate is low. So it is very important to improve relevant propaganda, education and training in gene testing.
出处
《现代生物医学进展》
CAS
2010年第5期925-928,共4页
Progress in Modern Biomedicine
基金
杭州市属高校重点实验室科技创新项目基金资助(20090233T07)
关键词
社区居民
基因检测
需求意愿
影响因素
Community residents, Gene testing, Intention, Impact factors
