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新型抗真菌药米卡芬净 被引量：4

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摘要 对米卡芬净的作用机制、抗菌谱、药动学、药物相互作用、临床疗效有效性和安全性评价以及不良反应和耐受性的有关研究进行了综述。
作者 董涛 王睿
机构地区 解放军总医院临床药理研究室
出处 《国外医药（抗生素分册）》 CAS 2006年第3期136-138,共3页 World Notes on Antibiotics
关键词 抗真菌药 棘白菌素 米卡芬净
分类号 R978.5 [医药卫生—药品]
  • 相关文献

参考文献18

  • 1Tomishima M, Ohki H, Yamada A, et al. FK463, a novel water-soluble echinocandin lipopeptides: synthesis and antifungal activity[ J]. J Antibiot, 1999,52:674
  • 2Hatano K, Morishita Y, Nakai T,et al. Antifungal mechanism of FK463 against Candida albicans and Aspergillus fumigatus[ J ]. J Antibiot,2002,55:219
  • 3Tawara S, Ikeda F, Maki K, et al. In vitro activities of a new lipopeptide antifungal agent, FK463, against a variety of clinically important fungi [ J ]. Antimicrob Agents Chemother,2000,44:57
  • 4Petraitis V, Petraitiene R, Groll A ,et al, Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits [ J ].Antimicrob Agents Chemother ,2002 , 46 ,1857
  • 5Ikeda F, Otomo K, Nakai T, et al. In vitro activity of a new lipopeptide antifungal agent, micafungin against a variety of clinically important fungi [ J ]. Jpn J Chemother,2002,50:8
  • 6Yamato Y,Kaneko H ,Yarnasaki S,et al. Distribution and excretion after intravenous dosing of C14-mieafunfin to rats[ J ]. Jpn J Chemother,2002,50:80
  • 7Andreas H, Groll, Diana Mickiene, Vidmantas Petraitis, et al. Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin ( FK463 ) in rabbits [ J ]. Antimicrob Agents Chemother,2001,45:3322
  • 8Azuma J, Nakahara K, Kagoyama A, et al. Phase I study of micafungin [ J]. Jpn J Chemother ,2002 ,50 : 104
  • 9Azuma J, Nakahara K, Kagoyama A, et al. Pharmacokinetic study of micafungin [ J ]. Jpn J Chemother ,2002 ,50 : 155
  • 10Townsend R, Terakawa M, Bekersky I. PK/disposition of 14C-FK463,a novel echinocandin antifungal, in male volunteers [ J ]. J Clin Pharmacol,2000 ,40:1017

同被引文献33

  • 1黄晓军.重视侵袭性真菌感染的诊治[J].中国实用内科杂志,2006,26(1):52-53. 被引量：11
  • 2肖怡,张淑华.棘白菌素类抗真菌药物米卡芬净的作用[J].国外医药（抗生素分册）,2006,27(6):255-261. 被引量：14
  • 3乔建军,刘伟,万喆,李若瑜.米卡芬净对分离自中国的念珠菌和曲霉临床株体外抑菌活性的研究[J].中国真菌学杂志,2007,2(1):5-9. 被引量：25
  • 4夏路风,李扬,傅得兴.棘白菌素类抗真菌药米卡芬净的药理与临床评价[J].中国新药杂志,2007,16(5):410-413. 被引量：19
  • 5Ikeda F.Antifungal activity and clinical efficacy of micafungin (funguard)[J].Jpn J Med Mycol,2005,46:217.
  • 6Tawara S,Ikeda F,Maki K,et al.In vitro activities of a new lipopeptide antifungal agent micafungin against a variety of clinically important fungi[J].Antimicrob Agents Chemother,2000,44(1):57.
  • 7Chandrasekar P H,Sobel J D.Micafungin:a new echiocandin[J].Clin Infect Dis,2006,42(8):1171.
  • 8Mary F H,Pharm D,Helen E S,et al.Pharmacokinetics of Micafuungin in healthy volunteers,volunteers with modertate liver disease,and volunteers with renal dysfunction[J].J Clin Pharmacol,2005,45:1145.
  • 9Dewet N,Llanoscuentas A,Suleiman J,et al.A randomized,double-blind,parallel group,dose response study of micafungin compared with fluconazole for the treatment of esophageal Candidiasis in HIV-positive patients[J].Clin Infect D is,2004,39(6):842.
  • 10Denning D W,Marr K A,Lau W M,et al.Micafungin(FK463),alone or in combination with other systemic antifungal agents,for the treatment of acute invasive aspergillosis[J].J Infect,2006,53(5):337.

引证文献4

二级引证文献19

国外医药（抗生素分册）
2006年 第3期

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