摘要
目的:探讨泌尿生殖系神经鞘瘤的临床、影像学及病理特点。方法:回顾性分析1994～2004年7例泌尿生殖系神经鞘瘤患者的临床资料,包括肾上腺、膀胱、前列腺、精索、阴囊及阴茎的神经鞘瘤,结合文献分析其特点。结果:患者平均年龄42岁,均为偶然发现或体检时发现,通过病理检查确诊。随访2～6年,7例患者肿瘤均经手术切除,病理证实6例良性,无复发;1例恶性睾丸神经鞘瘤,2年后死于肿瘤复发转移。结论:手术切除是目前治疗泌尿生殖系统神经鞘瘤的方法,由于泌尿生殖系神经鞘瘤缺乏典型的临床表现,临床诊断困难,确诊需经病理学诊断。肿瘤特异性标志物S100,Leu7及MBP有助于该病的诊断。
Objective：To study the clinical features of schwannoma in the genitourinary system. Methods：Seven patients with genital schwannoma admitted from 1994 to 2004 were reviewed. The lesions were located in the adrenal gland,kidney, bladder, prostate, spermatic cord, testis, scrotum or penis. Tumors were simply resected in 5 patients and radically eradicated in two. Results： The average age of the cohort was 42 years. The most common sign at presentation was a palpable genital mass accidentally discovered by the patient or detected by the physician during a physical check. Diagnosis was made through postoperative pathological examination. Follow-up ranged from 2 years to 6 years （mean 4.5）. Six cases were cured by simple excision and 1 patient with malignant testis schwannoma died of recurrence 2 year after surgery. Conclusions： Tumor resection is the treatment of choice for schwannoma,owing to the lack of characteristic clinical manifestation, the final diagnosis relys on postoperative pathological examination. S-100 Leu-7 and MBP are useful markers for the diagnosis of schwannoma.
出处
《临床泌尿外科杂志》
2006年第5期358-359,共2页
Journal of Clinical Urology
