摘要
用于肾癌分子靶向治疗研究常用的靶点包括具有靶向性的表皮生长因子受体(EGFR)阻断剂、抗肿瘤血管生成的药物、针对某些特定细胞标志物的单克隆抗体、针对某些癌基因和癌细胞遗传学标志的药物以及基因治疗等。
出处
《国际泌尿系统杂志》
2006年第3期306-309,共4页
International Journal of Urology and Nephrology
参考文献18
-
1Baselga J,Arteaga CL.Critical update and emerging trends in epidermal growth factor receptor targeting in cancer.J Clin Oncol,2005,23:2445-59.
-
2Bukowske RM.Epidermal growth factor receptor expression in renal cell carcinoma:rationale for therapy with sidling blockade.Curr Oncol Rep.2005,7:87-89.
-
3Sumitomo M,Asano T,Asakuma J,et al.ZD1839 modulates paclitaxel response in renal cancer by blocking paclitaxel-induced activation of the epidermal growth factor recptor-extracellular signal-regulated kinase pathway.Clin Cancer Res.2004,10:794-801.
-
4Sato K,Kakinum H.Quantitiative analysis of gene expressions of vascular endothelial growth factor-related factors and their receptors in renal cell carcinoma.Tohoku J Exp Med,2001,195:101-113.
-
5Yang JC,Haworth L,Sherry RM,et al.A randomized trial of vacizumab,an anti-vascular endothelial growth factor antibody for metastatic renal cancer.N Engl J Med,2003,349:427-434.
-
6Potter CP,Harris AL.Diagnostic,prognostic and therapeutic implications of carbonic anhydrases in cancer.Br J Cancer,2003,89:2-7.
-
7Stadick H,Stockmeyer B,Kuhn R,et al.Epidermal growth factor receptor and g250:useful target antigens for antibody mediated cellular cytotoxicity against renal cell carcinoma? J Urol.2002,167:707-712.
-
8Bleumer I,Knuth A,Oosterwijk E,et al.A phase 2 trial of chimeric monoclonal antibody G250 for advanced renal cell carcinoma paients.Br J Cancer,2004,90:985-990.
-
9Kassis AI,Adelstein S J,Mariani G.Radiolabeled nucleoside analogs in cancer diagnosis and therapy.J Nucl Med,1996,40:301-319.
-
10郑骏年,孙晓青,陈家存,温儒民,李望,刘俊杰.^(125)I偶联Ki-67反义核酸对人肾癌细胞生长及凋亡的调控作用[J].中华实验外科杂志,2004,21(3):290-291. 被引量:7
共引文献6
-
1郑骏年 ,陈家存 ,孙晓青 ,孙亚峰 ,顾骧 ,温儒民 ,李望 ,吴松 ,刘俊杰 .Ki67反义核酸对裸鼠人肾癌细胞移植瘤生长及凋亡的影响[J].中华实验外科杂志,2004,21(9):1132-1133. 被引量:4
-
2郑骏年,孙晓青,陈家存,孙亚峰,温儒民,薛松,吴松,刘俊杰,胡书群.Ki67反义多肽核酸抑制肾癌生长的体外及动物实验研究[J].现代免疫学,2005,25(2):149-151. 被引量:3
-
3郑骏年,马腾骧,孙晓青,陈家存,温儒民,曹敬毅,杨文发,李望,刘俊杰.Ki-67基因siRNA表达质粒的构建、鉴定及功能研究[J].中华实验外科杂志,2005,22(5):611-613. 被引量:11
-
4郑骏年,马腾骧,孙晓青,陈家存,吴松,李望,刘俊杰.^(125)I偶联反义核酸对裸鼠肾癌移植瘤的治疗作用[J].中华泌尿外科杂志,2005,26(10):679-682. 被引量:3
-
5蔡守良.针刺发动宫缩50例观察[J].中国针灸,1999,19(10):596-596.
-
6程欢,张炜,王增军,苏建堂.肾透明细胞癌中胰岛素样生长因子2外显子9异常甲基化与其表达的关系[J].中华实验外科杂志,2012,29(3):495-497. 被引量:2
同被引文献15
-
1郭三维,董柏君,黄翼然.肾癌预后分析的研究进展[J].国际泌尿系统杂志,2006,26(3):309-315. 被引量:12
-
2张秉鸿,王晓雄.肿瘤内淋巴管形成与肿瘤转移研究进展[J].国际泌尿系统杂志,2006,26(6):785-789. 被引量:1
-
3刘利维,韩瑞发,刘春雨.保留肾单位手术和肾癌根治术治疗小肾癌疗效比较的Meta分析[J].中华泌尿外科杂志,2007,28(10):668-370.
-
4Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015 [ J]. CA Cancer J Clin ,2015,65 ( 1 ) :5 - 29. DOI : 10. 3322/caac. 21254.
-
5Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2009 [ J ]. CA Cancer J Clin,2009,59 (4) : 225 - 249. DOI : 10. 3322/caac. 20006.
-
6Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012 [ J]. CA Cancer J Clin,2012,62 ( 1 ) : 10 - 29. DOI: 10. 3322/caac. 20138.
-
7Ljungberg B, Bensalah K, Canfield S, et al. EAU guidelines on renal cell carcinoma: 2014 update [ J ]. Eur Urol, 2015,67 ( 5 ) : 913 -924. DOI:10. 1016/j. eururo. 2015.01. 005.
-
8Kutikov A, Uzzo RG. The R. E. N. A. L, nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth [ J ]. J Urol, 2009,182 ( 3 ) : 844 - 853. DOI: 10. 1016/j. jure. 2009.05. 035.
-
9Ficarra V, Novara G, Seeco S, et al. Preoperative aspects and dimensions used for an anatomical (PADUA) classification of re- nal turnouts in patients who are candidates for nephron - sparing surgery[J]. Eur Urol,2009,56(5) :786 -793. DOI:IO. 1016/ j. eurure. 2009.07. 040.
-
10Zhou L, Guo J, Wang H, et al. The Zhongshan score: a novel and simple anatomic classification system to predict perioperative outcomes of nephron - sparing surgery [ J ]. Medicine ( Balti- more) ,2015,94(5) :e506.10. 1097/MD. 0000000000000506.
引证文献2
-
1熊祖泉,董国伟,郑捷,冯陈陈,方祖军,丁强,于洋.肾细胞癌手术切除方式变更的人群特征及其影响[J].国际泌尿系统杂志,2016,36(3):373-376.
-
2苗宝磊,甘卫东.淋巴管新生与肾细胞癌诊疗关系的研究进展[J].国际泌尿系统杂志,2016,36(6):920-923.
-
1孙超,沈云峰,李建勇.与急性髓系白血病预后相关的基因过表达[J].实用医学杂志,2009,25(16):2782-2783.
-
2孙建刚,刘仙明.肺癌分子靶向治疗新进展[J].肿瘤基础与临床,2008,21(4):367-368. 被引量:1
-
3周健强,雷伟.急性早幼粒细胞白血病的治疗现状及进展[J].海南医学,2008,19(8):153-155. 被引量:2
-
4王紫齐,吴迪炯,叶宝东,邵科钉,周郁鸿.自噬途径在急性早幼粒细胞白血病中作用及其调控机制研究进展[J].临床血液学杂志,2016,29(3):421-424. 被引量:2
-
5赵新汉,田洪刚.肿瘤的分子靶向治疗[J].现代肿瘤医学,2005,13(1):133-136. 被引量:3
-
6刘永哲,鞠桂芝.DNA甲基化与电离辐射效应[J].中华放射医学与防护杂志,2009,29(3):338-340. 被引量:2
-
7郭福晓,李攀,陈红梅,夏成青,程建兵,邹媛,高娟.伴双重t(15;17)易位的四倍体急性髓系白血病一例并文献复习[J].中华临床医师杂志(电子版),2015,9(18):115-118. 被引量:2
-
8朱熙君,李梅君,金洁萍.急性早幼粒细胞白血病的治疗进展[J].中国误诊学杂志,2006,6(23):4529-4531. 被引量:2
-
9申建凯,张广森,肖乐,裴敏飞,徐运孝.慢性粒细胞白血病细胞遗传学特征分析[J].湖南医科大学学报,2003,28(4):431-432.
-
10刘旭军,周晋,赵艳红,杨昆鹏,侯宇航.慢性粒细胞白血病耐药机制及治疗策略[J].现代生物医学进展,2014,14(5):975-977. 被引量:7