摘要
目的:观察踝臂指数测量值(AB I)对国人冠状动脉狭窄程度及冠心病病人预后的预测价值。方法:选取121例行冠状动脉造影的患者进行AB I测量、病史收集、生化检查和统计学处理,观察AB I、临床指标与冠状动脉造影结果的相关性。并随访14.2±2.4个月,观察AB I与心血管事件(心源性死亡、非致死性心肌梗死、不稳定性心绞痛、冠状动脉旁路移植术)的相关性。结果:冠状动脉造影严重病变组和非严重病变组间AB I有显著差异;AB I降低组与AB I正常组间心血管事件发生率有显著差异。结论:AB I<0.9对冠状动脉严重病变(三支和左主干病变)及冠心病患者的预后有预测价值。
Objective： Resting ankle - brachial pressure index （ABI） is a noninvasive method to assess the patency of the lower extremity arterial system. This study aimed to examine the relation between ABI and the extent of coronary atherosclerosis, the extracoronary atherosclerosis lesions, and the prognosis of patients referred for elective coronary angiography. Methods：One hundred twenty - one consecutive patients underwent coronary angiography, and ABI evaluation; subjects were followed up for 14.2 ± 2.4 months. Results： With regard to vascular risk factors, only age （ p = 0.039 ） , smoking （ p = 0.025 ） and diabetes （ p = 0.026） were related to ABI in the multiple regression analysis. ABI was related to the extent of coronary artery disease as measured by number of coronary arteries diseased. In the follow - up study ABI 〈0. 90 was a univariate predictor of cardiovascular events （ cardiac death, nonfatal myocardial infarction, unstable angina） and revascutarization procedures. Conclusions： ABI is a simple index related to the extent of atherosclerosis in coronary and noncoronary arterial beds, reflecting generalized atheroscterosis. ABI could be useful in assessing the risk for cardiovascular events in patients with coronary artery disease.
出处
《中国民康医学》
2006年第9期340-343,共4页
Medical Journal of Chinese People’s Health
