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上海地区婴儿出生时骨定量超声值与白人婴儿的比较 被引量:6

Comparison of the quantitative ultrasound bone measurements between Shanghai and Caucasian infants at birth
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摘要 目的评价定量超声技术的临床实用性,比较上海地区和高加索白人婴儿出生时骨状况。方法采用以色列Sunlight公司生产的Omnisense定量超声仪,对157例新生儿进行胫骨声波速度(speed of sound,SOS)测量并与白人婴儿比较。结果上海地区男女婴儿之间SOS值差别无统计学意义[男88例,SOS值为(2968±115)m/s;女69例,SOS值为(2956±105)m/s;P= 0.524]。早产儿68例,平均胎龄(33.0±2.5)周,SOS值平均为(2935±96)m/s,足月儿89例,平均胎龄(39.4±1.3)周,SOS值平均为(2984±116)m/s,早产儿SOS值显著低于足月儿(t=2.837,P= 0.005)。与白人婴儿比较,上海地区婴儿胫骨SOS值低于白人,其SOS的差距(定义为Z值)在女婴 (-0.81±0.92)比男婴(-0.55±0.97)明显,(P<0.05),在足月儿(-0.80±1.03)比早产儿(-0.50 ±0.83)明显,在正常出生体重的婴儿比低出生体重的婴儿明显,但尚无统计学意义(P均>0.05)。结论 QUS适用于婴儿骨状况的评价;上海地区婴儿出生时骨强度可能低于高加索白人,此差距在妊娠晚期变得明显。 Objective To compare the bone status between Shanghai and Caucasian infants at birth by quantitative ultrasound (QUS) and evaluate its clinical application. Methods An ultrasound bone sonometer, Omnisense (Sunlight Medical Ltd, Israel), was used to measure the bone speed of sound (SOS) of tibia in 157 Shanghai infants, and then compared with those of Caucasian. Results No significant difference of SOS was found between male In= 88, (2968±115) m/s] and female infants [n=69, (2956±105) m/s](P=0. 524). The SOS of premature infants [(2935±96) m/s] was lower than that of full-term infants [2984± 116) m/s] (P= 0. 005). Comparing with Caucasian infants, the tibial SOS was lower in Shanghai infants. The differences of SOS, which were defined as Z- Score, in Shanghai infants were more remarkable in female infants (-0. 81±0.92 Z-Score) than that of male (-0. 55±0.97 Z-Score), and in full-term infants (-0. 80± 1.03 Z-Score)than in premature infants (-0.50± 0. 83 Z-Score), and in infants with normal birth weight than in infants with lower birth weight. Conclusions QUS is suitable for evaluating bone status in infants. Shanghai infants have lower bone strength than Caucasian's and the difference becomes more significant in the last trimester.
出处 《中华围产医学杂志》 CAS 2006年第2期108-111,共4页 Chinese Journal of Perinatal Medicine
关键词 要儿 新生 要儿 早产 超声检查 产前 胫骨 Infant, newborn Infant, premature Ultrasonography, prenatal Tibia
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