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HBV前S1蛋白在乙型肝炎中的临床意义 被引量:2

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摘要 目的了解HBV感染者血清中PreS1蛋白与HBV-DNA之间的关系,以及对乙型肝炎诊断的价值。方法应用ELISA方法对739例血清进行HBVM检测(包括PreS1蛋白),并与HBV-DNA荧光定量PCR检测结果比较分析。结果在HBsAg(+),HBeAg(+),HBcAb(+)模式中PreS1、HBV-DNA的阳性检出率分别为69.3%和97.6%,PreS1的总检出率为36.3%,HBV-DNA的总检出率为58.7%,经过对二者的配对χ2检验,两者有显著性差异(P<0.005),经过相关回归分析,r=0.8732,y=-9.9534+1.2553x。结论PreS1、HBV-DNA的阳性检出率呈显著正相关,PreS1蛋白可作为HBV感染的重要指标。
出处 《四川医学》 CAS 2006年第5期486-487,共2页 Sichuan Medical Journal
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参考文献5

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