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磷脂酶A_2在炎症反应中的作用 被引量:17

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摘要 磷脂酶A2是一类催化磷脂二位酰基水解的酶族,主要分为三种类型:分泌型、胞浆型、非钙离子依赖型,其结构特点的差异导致其功能千差万别.磷脂酶A,参与多种急、慢性炎症反应,是花生四烯酸、溶血磷脂等炎性介质生成的限速酶.他促进了一系列炎性介质和细胞因子的大量释放和激活,在炎性病变的发生和发展过程中起重要的作用,直接影响其发展和预后.
出处 《世界华人消化杂志》 CAS 北大核心 2006年第8期795-799,共5页 World Chinese Journal of Digestology
基金 国家自然科学基金资助项目 No.30300465 武警医学院科研基金资助项目 No.WY2002-19
关键词 磷脂酶A2 炎症
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