摘要
Recent years have witnessed tremendous progress in our understanding of irritable bowel syndrome （IBS）. It is evident that this is a truly global disease associated with significant symptoms and impairments in personal and social functioning for afflicted individuals. Advances in our understanding of gut flora-mucosal interactions, the enteric nervous system and the brain-gut axis have led to substantial progress in the pathogenesis of symptoms in IBS and have provided some hints towards the basic etiology of this disorder, in some subpopulations, at the very least. We look forward to a time when therapy will be addressed to pathophysiology and perhaps, even to primary etiology. In the meantime, a model based on a primary role for intestinal inflammation serves to integrate the various strands, which contribute to the presentation of IBS
最近的年在我们急躁的肠症候群(IBS ) 的理解见证巨大的进步。这是在个人并且为折磨的个人的社会工作与重要症状和缺陷联系的真正全球的疾病，是明显的。在我们内脏 flora-mucosal 相互作用，伤寒神经系统和大脑勇气轴的理解的进展至少在 IBS 在症状的致病导致了实质的进步并且向这混乱的基本病原学提供了一些提示，在一些潜水艇人口。我们盼望治疗将针对病理生理学并且也许的一时间，甚至到主要病原学。同时，一个模型基于为肠的发炎的一个主要角色服役集成各种各样的海滨，它贡献 IBS 的演讲。
