摘要
目的:探明卵巢激素水平变化在经前期综合征(PMS)特定亚型发病机理中的作用与影响,揭示PMS肝气逆证部分微观机制。方法:采用放射免疫法检测月经周期不同时相雌二醇(E2)、孕酮(P)含量的动态变化。结果:PMS肝气逆证组E2、P卵泡期分泌峰值明显减低,黄体期的分泌峰值未有形成。结论:E2、P卵泡期分泌高峰的低平与黄体期分泌峰的阙如是PMS肝气逆证微观机理之一。PMS特定亚型病理生理机制之一可能是E2、P水平持续性低下。
To probe into the role of changes of ovarian hormones in pathogenesis of the specific subgroup of prementrual syndrome （PMS） and reveal partial microcosmic mechanisms of invasion of the hyperative liver-qi. Methods：Radioimmunoassay was used to determine dynamic changes of estradiol （E2） and progesterone （P） levels at different stages of menstrual cycle. Results：In the group of invasion of the hyperactive liver-qi ,the secretive peak value of E2 and P in the follicular phase decreased significantly, and the secretive peak value at the luteal phase did not form. Conclusion： Low E2 and P secretive peak at the follicular phase and lack of secretive peak at the luteal phase is one of the micro-mechanisms of PMS with invasion of the hyperactive liver-qi. Continuous Lower level of E2 and P is possibly a pathophysiolocal characteristics of special subgroup of PMS.
出处
《中医杂志》
CSCD
北大核心
2006年第4期295-297,共3页
Journal of Traditional Chinese Medicine
基金
国家中医药管理局资助课题[2000-J-Z(PMQB)]
关键词
经前期综合征
血液雌二醇
血液
肝气逆证
Premenstrual Syndrome/blood
Estradiol/blood
@ syndrome of invasion of the hyperactive liver-qi
