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脊髓损伤大鼠的阴茎海绵体肌电图研究 被引量:3

CC-EMG in conscious spinal cord injured rats
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摘要 目的探讨海绵体肌电图诊断脊髓性勃起功能障碍的价值。方法将24只成年雄性SD大鼠(300~400 g)分成:对照组、T9和L6损伤组(每组8只)。损伤脊髓1周后,用肌电图仪采集注射阿朴吗啡前后阴茎肌电数据,采集频率20~3 000 Hz、扫描速度5 ms/d、灵敏度10 μV/d。用t检验方法分析统计数据。结果对照组使用阿朴吗啡10 min均方根振幅为(5.60±0.89)μV, 大于T9损伤组(3.60±1.14)μV(P<0.05);使用阿朴吗啡前、使用后5 min和10 min高/低功率比均为0.05±0.03,小于L6损伤组0.13±0.04、0.15±0.07、0.13±0.07(P<0.05)。T9损伤组使用阿朴吗啡后5 min和10 min平均频率分别为(122.40±47.99)、(151.80±76.42)Hz,较L6损伤组(278.83±118.66)、(265.00±81.35)Hz低(P<0.05)。结论海绵体肌电图对脊髓性勃起功能障碍有诊断价值。 Objective To investigate the value of EMG of corpus eavernosum (CC-EMG) in diagneais of erectile dysfunction after spinal cord injury. Methods Twenty-four male adult SD rats were divided into three groups equally: controls, thoracic cord injured (T9) and lumbar cord injured (L6) groups. After one week of being spinal cord injured, aU experimental rats underwent CC-EMG with a cutoff frequency of 20-3000Hz, an amplitude of ±10μV and a monitor speed time of 5 ms/d under apomorphine s. c. Results Root mean square of the controls was (5.60 ± 0.89)μV, greater than (3.60 ± 1.14)μV in the thoracic cord injured at 10 min.High/low power around 1400/140 Hz of the controls was 0.05±0.03, less than that of the lumbar cord injured before and at 5 min and 10 min. Mean frequency of the thoracic cord injured was (122.40 ± 47.99), (151.80 ±76.42)Hz, lower than (278.83 ± 118.66), (265.00 ± 81.35) Hz of the lumbar ones 5 min and 10 min respectively after apomorphine s. c. (P〈0.05). Conclusion It is possible to develop CC-EMG to diagnose spinal cord injured erectile dysfunction.
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2006年第5期566-567,共2页 Chinese Journal of Experimental Surgery
基金 湖北省科技攻关资助项目(2005AA301C17)
关键词 脊髓损伤 海绵体 肌电图 Spinal cord injury Corpus eavernosum EMG
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二级参考文献3

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