摘要
目的:检测四种种植临床常用植骨材料的蛋白吸附能力,并与其物理结构进行对照研究,为临床选用植骨材料提供参考。方法:使用微晶分析仪和扫描电镜分别测定四种植骨材料:Bio-Oss、PepGen-15、Algipore和PerioGlas的比表面积、孔容积和表面形态,并分别将材料加入人血浆中,采用半定量法测定上清液中纤维蛋白原(Fib)的浓度,进行对照研究。结果:Bio-Oss具有最大的比表面积和孔容积,加入四种材料后血清Fib浓度均发生了不同程度的变化。结论:具有不同物理结构的植骨材料对蛋白的吸附能力不同,临床应根据其吸附特性进行操作。
Objective： The capability of plasma protein adsorption to the four bone - substitutes in common use were detected and researched in comparison with physical structure, in favor of choosing the bone - substitute in clinic. Methods： The BET surface areas and pore volume of Bio- Oss, PepGen- 15, Algipore and PerioGlas were mensurated by the crystallite analyzer respectively . And the surface structures of the four substitutes were observed by the scanning electron microscope （SEM）. Simultaneously, the fibrinogenic concentration in the single plasma and the plasmas mixing with four bone - substitutes were mensurated by the halfquantitative method. Result： The largest BET surface and pore volume were observed in Bio - Oss. Moreover, in comparison with the single plasma, the changes happened to all the fibrinogenic concentrations after mixing with the bone - substitutes. Conclusion： The capability of plasma protein adsorption of the four bone - substitutes are different due to their different physical structures; it is feasible for depending on the adsorption in the clinical operation as well.
出处
《中国口腔种植学杂志》
2006年第1期9-12,共4页
Chinese Journal of Oral Implantology
基金
上海市科委启明星培养计划(03QD14056)
关键词
植骨材料
蛋白吸附
纤维蛋白原
表面结构
Bone- substitute
Protein adsorption
Fibrinogen
Surface structure
