摘要
宫颈癌在妇科恶性肿瘤中占首位，死亡率占第二位。我院自１９９２年～１９９４年收治宫颈癌５６例，有２９例行术前化疗，其中Ⅱ＿ａ期１１例，Ⅱ＿ｂ期１５例，Ⅲ＿ａ期２例，Ⅳ期１例。化疗方案为宫颈癌组织局部用５—Ｆｕ或平阳霉素，静脉用ＥＤＶＢ方案３天，２周１次为１疗程，用１～３疗程，使癌组织明显缩小，周围组织变软，为原来无法手术的病人创造了手术根治的机会。化疗后常有消化道反应、脱发、骨髓抑制，术后并发症有膀胱麻痹、淋巴囊肿、血栓性静脉炎等。为提高治愈率术后要继续化疗，有淋巴转移者可做放射治疗。
Cervical cancers rank first in the gynecological carcinoma and its mortality ranks second. 56 patients with cervical cancers were admitted and treated in our hospital from Feb. 1992 to Oct. 1994, 29 were treated by chemotherpy before operation. of them , 11 cases were in stage Ⅱa, 15 in stage Ⅱb, 2 in stage Ⅲa and 1 in stage Ⅳ. The chemotherapy method was as follows: covering the carcinoma surface by 5-fluorouracil or injecting blemycinia into the carcinoma, using epipoduyllotoxin (Vp-16), cispcatin (PPD), Vincristire and blemycinia combinally for the whole body for 3 days. Once every weeks being a course. After 1-3 courses,the cervical carcinoma shrank obviously and the parametrium became soft. This offered a good a chance of radical hysterectomy for the patients who could not be operated on previously. Sideeffects after chemotherapy were digestive reaction,alopecia and bone marrow inhibition. Postoperative complications were cystoparalysis, lymphaderocyst, thrombophlebitis, etc. To increase the curative effect,chemotheray can be apllied after operation,and radiotherapy can be used in the patierts with lympha-transportation.
出处
《河南肿瘤学杂志》
1996年第3期191-193,共3页
Henan Journal of Oncology
