摘要
目的 :观察恩丹西酮预防以顺铂为主肺癌化疗所致呕吐的疗效。方法 :用顺铂化疗前后5min内分别静脉用8mg恩丹西酮 ,次日继续用8mg;对照组则于顺铂化疗前后5min内分别静脉用甲氧氯普胺10mg,次日继续用10mg,观察两组疗效。结果 :恩丹西酮组第1～3天对恶心、呕吐的控制率分别为95 7 %、91 3%、87% ,明显高于甲氧氯普胺组20 %、35 %、25%。(P<0 01)结论 :恩丹西酮预防以顺铂为主的肺癌化疗所致的恶心。
Objective:To observe the Curative Effects of Ondansetron Hydrochlori de and Metoclopramide Dihydrochloride applying to prevent vomit which caused by Ch emotherapy(CDDP) of Lung Cancer.Methods:5 minutes before and after the patients of lung cancer were given Chemotherapy,intravenous treatment of Ondansetron Hydr ochloride and Metoclopramide Dihydrochloride were given to them separately in th e different group,to observe the incidence of vomit.Results:The effectiveness ra tios for Ondansetron Hydrochloride group in the 1st,2nd and 3rd days were 95 7 %,91 3%,87%;those for Metoclopramide Dihydrochloride group were 20%,35%,25 %(p<0 01).Conclusions:The Curative Effect of Ondansetron Hydrochloride applyin g to prevent vomit which caused by Chemotherapy(CDDP) of Lung Cancer is better t han that of Metoclopramide Dihydrochloride.
出处
《大理学院学报（综合版）》
CAS
2002年第3期21-22,共2页
Journal of Dali University
关键词
恩丹西酮
甲氧氯普胺
预防
肺癌
化疗
呕吐
副反应
疗效
Ondansetron hydrochloride
Metoclopramide dihydrochloride
Chemothera py
Side effect
