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终末器官对神经再生影响的实验研究 被引量:4

Influence of end organs on peripheral regeneration :an experimental study
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摘要 探讨神经远端终末器官对神经再生的影响。方法:采用硅胶管桥接大鼠双侧坐骨神经,一侧硅胶管套接的远端神经连有终末器官,另一侧远端神经不连有终末器官。术后2、4、6周取标本,通过肉眼观察、光镜、电镜和轴突图象分析仪观察神经再生情况。结果:从各时间段的标本检测,在再生神经干直径,有髓纤维的密度、数目,远端神经的面积及形态学比较,两者均无显著差异。结论:远端神经连有终末器官与否虽不是影响神经能否再生的关键因素。 The sciatic nerves of adult rats were transected and the cut ends of the transected nerves were placed in silicone tubers. On one side the distal nerve was connected with the end organs and on the contralateral side not connected with the end organs. After 2 .4.6 weeks, the rais were killed and the chambers together with adjacent nerve segments were removed for macroscopic, histologic and morphometric analysis. The results showed that the presence of the end organs influenced eventual maturation of nerve regeneration and the end organs were not essential to successful regeneration.
出处 《中华手外科杂志》 CSCD 1996年第1期41-43,共3页 Chinese Journal of Hand Surgery
关键词 神经再生 终末器官 硅胶管 实验 Nerve regeneration End organ Silicone tube
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参考文献1

  • 1F. Scaravilli. The influence of distal environment on peripheral nerve regeneration across a gap[J] 1984,Journal of Neurocytology(6):1027~1041

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