摘要
以微量生化法测定１５９例各年龄组的正常对照、良性胃病、胃癌患者血浆６种维生素及２２例胃癌手术标本各部位粘膜细胞内４种维生素、３０例慢性萎缩性胃炎胃镜活检粘膜细胞内β－胡萝卜素的含量。结果发现，正常健康老人和老年胃癌患者维生素Ｂ１２含量低于同组中青年人（Ｐ＜０．０５）；老年胃癌患者血浆β－胡萝卜素水平明显低于良性胃病和健康对照组（Ｐ＜０．０５）。胃癌患者癌区粘膜细胞内β－胡萝卜素与外周正常区域细胞内含量之差及慢性萎缩性胃炎活检粘膜细胞内的含量皆与年龄呈负相关。说明老年胃病患者血浆维生素的改变以维生素Ｂ１２和β－胡萝卜素为主；胃癌区粘膜细胞内β－胡萝卜素的降低幅度不如中青年明显，而老年慢性萎缩性胃炎患者该维生素又低于中青年。
n order to study further the alteration of plasma and gastric mucosa intracellular vitamin levels in elderly patients with gastric diseases, we determined the plasma vitamin concentrations in 114 cases with benign gastrosis, chronic atrophic gastritis (CAG), gastric ulcer (GU), gastric carcinoma(GC) and 45 controls, and the intracellular vitamin levels in the gastric mucosa in 22 cases with GC and 30 cases with CAG.The results showed that the level of plasma VB 12 in the controls and in the elderly GC palients was significantly lower than those in the corresonding middle aged and young patients ( P <0 05), and the level of β carotene(β C)in cases with GC was significantly lower than those in benign gastrosis patients and controls( P <0 05). The level of β C in the gastric mucosa from GC was relatively higher than those in the middle aged and young patients, but that from CAG was significantly lower than that in the young patients. The paper suggested that there were changes in plasma and intracellular vitamin concentrations in elderly gastrosis patients.
出处
《实用老年医学》
CAS
1996年第1期26-27,共2页
Practical Geriatrics
基金
国家自然科学基金
