摘要
为了解脑膜瘤的病理学改变与瘤周脑水肿的关系，我们对１３２例脑膜瘤病人的病理切片及２１例电镜检查结果进行了分析。结果发现：合体型、间变型及血管型脑膜瘤易伴重度瘤周水肿。瘤周水肿明显者，病理见肿瘤增殖活跃的表现。肉瘤型、间变型均见于中重度水肿组，非典型型重度水肿者显著高于良性型。若肿瘤血管成分增多，无砂粒体，可见血管外皮细胞易伴瘤周水肿。超微结构见水肿明显者，细胞核增大，核膜溶解，细胞内及细胞外水肿，线粒体溶解，粗面内质网扩张，溶酶体增多。中重度水肿者并可见分泌一排泄现象。
In order to find out the significance of certain pathological characteristics of meningioma and their relation with peritumoral edema, the histological sections of 132 cases of meningioma as well as ultrastructural characteristics in 21 patients were observed.Meningiomas with severe peritumoral edema were mostlikely tumors classified as syncytial,anaplastic or vascular types. Severe peritumoral edema was frequently associated with active proliferation,increased vascularlty and pericytes.On ultrastructural examination,enlargement of nuclei.dissolution of unclear membrane,intra-and extracellular edema,swollen and dissolved mitochondria,dilated rough endoplasmic reticulum,increased lysomes and secretory-excretory phenomenon(SEP) were commonly seen in tumors with moderate and severe peritumoral edema.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第7期486-490,共5页
Chinese Journal of Clinical Oncology
关键词
脑膜瘤
病理学
瘤周脑水肿
Meningioma
Peritumoral edema
Histology
