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立普妥治疗老年颈动脉粥样硬化疗效观察 被引量:3

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摘要 将94例颈动脉粥样硬化斑块形成患者随机分为1、2、3组(32例、30例、32例)。1组口服阿司匹林50m g/d,2组口服立普妥10m g/d,三组同时服用上述两种药物,剂量不变。治疗后6个月和2a行彩色多普勒超声检查,观察各组颈总动脉后壁中—内膜厚度(IM T)及双侧颈总动脉、颈内动脉、颈外动脉粥样斑块数量、类型。结果2、3组颈总动脉IM T和动脉粥样斑块数量均显著小于1组(P<0.05,<0.01);动脉粥样斑块类型改善情况优于1组(P<0.05,<0.01)。结论证实立普妥可显著促进动脉粥样硬化斑块消退,与阿司匹林联用,效果更佳。
出处 《山东医药》 CAS 北大核心 2006年第8期36-37,共2页 Shandong Medical Journal
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  • 1Casserly IP,Ziadak,Kapadia,S,et al.Impait of nonmeasuable borders and Variation in cross-Section Counts on intravascular Ultrasound measurement of atherosderofic Plaque voleme[J].Am J Cardiol,2002,(8)9:169-173.
  • 2haar JA,de Korte CL,Mastik F,et al.Effect of femperature Tncrease and freezing on intravascular elastography[J].Ultra-sonics,2002,40(5):879-881.
  • 3Masunori M.Detection of vunerable atherosclerotic plaque by int-ravascular ultrasound.The 13thcongress of the internation-alcardiac Doppler[J].society,2002,9.
  • 4Davies MJ.Pathophysiology of acate coronary Syndromes[J].Heat,2000,8(3):361-366.

同被引文献43

  • 1罗助荣,盖晓波.不稳定性心绞痛患者调脂干预对颈动脉粥样硬化及C反应蛋白的影响[J].中华心血管病杂志,2004,32(11):977-980. 被引量:40
  • 2白向东,杜秦川.阿托伐他汀治疗颈动脉粥样硬化疗效观察[J].宁夏医学杂志,2006,28(4):286-287. 被引量:1
  • 3杨丽平,刘丽文,钱蕴秋,杨力军,李兰荪,何光彬,周晓东,沈敏.阿托伐他汀对冠心病患者颈动脉内-中膜厚度的影响[J].西北国防医学杂志,2007,28(2):104-106. 被引量:6
  • 4杨宝峰.药理学[M].第7版.北京:人民卫生出版社,2008:135-136.
  • 5陆再英,钟南山.内科学[M].第7版.北京:人民卫生出版社.2008:251.
  • 6Nissen SE,Tuzcu EM,Schoenhagen P,et al. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial[J]. JAMA,2004, 291 (9): 1071-80.
  • 7Vaughan CJ,Delanty N. Neuroprotective properties of statins in cerebral ischemia and stroke[J]. Stroke, 1999,30(9): 1969-73.
  • 8Schonbeck U,Gerdes N,Varo N,et al. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells[J]. Circulation,2002,106(23):2888-93.
  • 9Motoyama K,Fukumoto S,Koyama H,et al. SREBP inhihits VEGF expression in human smooth muscle cells[J]. Biochem Biophys Res Commun,2006,342( 1):354-60.
  • 10Wong M,Edelstein J,Wollman J,et al. Ultrasonic-pathological comparison of the human arterial wall.Verification of intima-media thickness[J]. Arterioscler Thromb,1993,13(4):482-6.

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