期刊文献+

肝硬化合并脾功能亢进病人肝移植术后脾静脉血流动力学及外周血细胞变化的观察 被引量:1

Changes of blood flow dynamics of spleen vein and number of blood cells in circulation after liver transplant in patients with hepatocirrhosis and hypersplenism
暂未订购
导出
摘要 目的评价肝移植术中是否需保留脾脏。方法应用彩色多普勒超声测量术前及术后第1、2及4周35例肝硬化合并脾亢病人脾脏的长径、厚径及脾门静脉管径、平均血流速度及峰值血流速度等并进行比较。同时期测量病人肝固有动脉管径及峰值血流速度、门静脉管径及血流速度,检测病人外周血细胞计数。结果术后病人脾脏缩小、脾门静脉平均血流速度及峰值血流速度、门静脉血流速度增加,外周血细胞计数上升,与术前相比有统计学差异(P<0.05)。结论肝移植术后脾功能亢进症状得到部分改善,这些症状的改善是否继续或有反复仍需进行长期的观察和研究。 [Objective] To decide saving spleen or not in liver transplant, we comPared changes of blood flow dynamics of spleen vein and number of blood cells in circulation before operation with that after operation. [Method] In 35 patients with hepatocirrhosis and hypersplenism, we used color Doppler flow imaging to measure the length and thickness of spleen, width and blood flow velocity of spleen vein before liver transplant compare with that in 1st week, 2nd week and 4th week after operation. At the same time width and blood flow velocity of liver artery in port of liver, width and blood flow velocity of portae vein, the number of blood ceils in circulation had been measured. [Results] After liver transplant, the volume of spleen decreased, the mean blood flow velocity of spleen vein and the number of blood cells in circulation increased. Those changes were different significantly compared with that before operation (P 〈0.05). [ Conclusion ] After liver transplant, the symptom of hypersplenism may be improved. But whether these good changes will go on or not still depend on long time obselving and studying.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2006年第6期891-893,共3页 China Journal of Modern Medicine
基金 广州市科技局科技攻关计划项目资助(No:2004Z3-E0371)
关键词 肝硬化 脾功能抗进 肝移植术 血流动力学 血细胞 hepatocirmhosis hypersplenism live transplant blood flow dynamics blood cells
  • 相关文献

参考文献10

  • 1HOELS JC.Portal hypertension.Graycitniek(ed):Princip lesandpracticeo fgastroenterology and hepatologylogy ed New York Clsevier Science.Publishing Coinc,1988:1225-1267.
  • 2黎芳,黎志良,林炳亮,谢奇峰.病毒性肝炎肝硬化与胆汁性肝硬化的血脂及载脂蛋白分析比较(英文)[J].中国现代医学杂志,2004,14(13):52-54. 被引量:10
  • 3GIBSON P,GIBSON R,DITCHFIELD M,DONLAN JD.Splenomegaly:an insensitive sign of portal hypertension[J].Aust NZ J Wed,1990,20:771-774.
  • 4DITCHFIELD M,GIBSON R,DONLAN PR.Duplex Doppler ultrasound signs of portal hypertension:relative diagnostic value of examination of paraumbilical vein,portal vein and spleen[J].Australas Radiol,1992,36:102-105.
  • 5PECK-RADOSAVLJEVIC M.Hypersplenism[J].Eur Jcastroenterol Hepatol,2001,13(4):318-323.
  • 6BASHOUR FN,TERAN JC,MULLEN KD.Prevalence of peripheral blood cytopenias(hypersplenism) in patients with nonalcoholic chronic liver disease[J].Am J Castroenterol,2000,95(10):2936-2939.
  • 7郑树森,主编.肝移植[M].第1版.北京.人民卫生出版社,2001:377-378.
  • 8刘全达,何振平.肝硬化合并脾功能亢进症的治疗现状和展望[J].现代实用医学,2003,15(5):273-276. 被引量:14
  • 9GOULIS J,CHAU TN,JORDAN S,et al.Thrombopoietin concentrations are low in patients with cirrhosis and thrombocytopenia and are restored after orthotopic liver transplantation[J].Gut,1999,44(5):754-758.
  • 10GULBERG V.Hepatol,2002,35:630-634.

二级参考文献10

共引文献22

同被引文献12

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部