期刊文献+

冠脉侧支血流分数与急性心肌梗死关系研究 被引量:1

Correlation between pressure-derived collateral fractional flow and acute myocardial infarction
原文传递
导出
摘要 目的研究侧支循环与急性心肌梗死(AMI)介入术(PCI)后左室功能变化之间的关系。方法AMI患者29例行急诊PCI,术中应用冠脉内压力导丝测定冠状动脉内压力,计算压力源性的侧支血流分数(PDCF),依据冠脉侧支血流是否充盈,以0.24为PDCF截值将样本分为两组,术后采用Simpson方法测定左室射血分数(LVEF)、左室收缩及舒张末期容积(ESV、EDV),并计算相关的容积指数(ESVI、EDVI)。结果两组患者的PDCF均与PCI术后30 d时的射血分数呈正相关(r=0.9,P<0.01)。结论冠脉内压力源性的PDCF可预测AMI时左室功能的恢复情况。 Objective To measure the pressure-derived collateral fractional flow(PDCF) in the patients with acute myocardial infarction(AMI) ,and to evaluate the correlation between PDCF and left ventricular recovery function after primary percutaneous coronary intervention(PCI). Methods The PDCF,determined by Pw/Pa,was measured in 29 patients with first AMI treated by primary PCI, who were devided into two groups by the PDCF = 0.24. Left ventricular ejection fraction(LVEF), end systolic volume(ESV) and end diastolic volume(EDV), and the related indexes were obtained by Simpson method after PCI. Results LVEF in both groups were significantly related to PDCF in the 30th day(R = 0.9, P 〈 0.01 ) after PCI. Conclusion The collateral blood flow, as measured by PDCF,can predict left ventricular recovery function after successful PCI.
出处 《中国基层医药》 CAS 2006年第2期212-214,共3页 Chinese Journal of Primary Medicine and Pharmacy
基金 2004年度广东省汕头市科技计划项目(2004066)
关键词 心肌梗死 左心室功能 侧支血流分数 冠脉侧支血流分数 急性心肌梗死 Myocardial infarction Ventricular function, left Collateral fractional flow
  • 相关文献

参考文献8

  • 1Piestrzeniewicz K, Navarm-Kuczborska N, Bolinska H, et al. The impact of comprehensive cardiac rehabilitation in patients up to 55 years old after acute myocardial infarction treated with primary coronary int ervention. Pol Arch Med Wewn, 2004,111 (3) : 309-317.
  • 2Sugiura T, Nakamura S, Kudo Y, et al. Clinical factors associated with persistent perieardial effusion after successful primary coronary angioplasty, Chest, 2005,128(2) : 798-803.
  • 3Rakhit RD,Seiler C, Wustmann K, et al. Tumour necrosis factor-alpha and interleukin-6 release during primary percutaneous coronary intervention for acute myocardial infarction is related to coronary collateral flow. Coron Artery Dis, 2005,16(3) : 147-152.
  • 4Smith RD, llzley CD. Clinical contribution of the collateral circulation to myocardial protection. Coron Artery Dis,2004,15(7) :393-398.
  • 5Koerselman J ,Jaegere PP, Verhaar MC, et al. Cardiac ischemic score determines the presence of coronary collateral circulation. Cardiovasc Drugs Ther,2005,19(4) :283-289.
  • 6Elsman P, Van' t Hof AW, Boer MJ, et al. Role of collateral circulation in the acute phase of ST-segment-elevation myocardial infarction treated with primary coronary intervention. Eur Heart J, 2004,25(10) :854-858.
  • 7欧知宏,方唯一,周旭晨,王珂,郑晓群,朱皓,蔡志雄,刘欣.急性心肌梗死患者侧支血流分数与左室重塑关系的临床研究[J].中国介入心脏病学杂志,2002,10(4):197-200. 被引量:5
  • 8Werner S, Ferrari M, Richartz B, et al. Microvascular dysfuntion in chronic total coronary occlusions. Circulation, 2001,104 ( 10 ) : 1129-1134.

二级参考文献11

  • 1[1]Nicolau JC, Nogueira PR, Pinto MAFV, et al. Department of Cardiology, Early infarct artery collateral flow does not improve long-term survival following thrombolytic therapy for acute myocardial infarction. Am J Cardiol, 1999,83:21-26.
  • 2[2]Gould KL, Lipscomb K, Hamilton GW. Physiologic basis for assessing critical stenosis: instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve. Am J Cardiol, 1974,33:87-94.
  • 3[3]Rentrop KP, Cohen M, Blanke H, et al. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty in human subjects. J Am Coll Cardiol, 1985,5:587-592.
  • 4[4]Patel BS, Jeroudi MO, O'Neill PG, et al. Effect of human recombinant superoxide dismutase on canine myocardial infarction. Am J Physiol, 1990,258:H369-H380.
  • 5[5]Schaper J, Weihrauch D. Collateral vessel development in the porcine and canine heart. In: Schaper W, Schaper J, editors. Collateral circulation. Boston: Kluwer, 1993.65-102.
  • 6[6]Vanoverschelde JLJ, Wijns W, Depre C, et al. Mechanisms of chronic regional postischemic dysfunction in humans: new insights from the study of noninfarcted collateral-dependent myocardium. Circulation, 1993,87:1513-1523.
  • 7[7]Elayda MA, Mathur VS, Hall RJ, et al. Collateral circulation in coronary artery disease. Am J Cardiol, 1985,55:58.
  • 8[8]Cohen MV. Morphological considerations of the coronary collateral cerculation in man. In: Coronary collaterals. New York: Futura Publishing Co, 1985.1-91.
  • 9[9]Pijls NHJ, Bech GJW, EI Gamal MIH, et al. Quantification of recruitable coronary collateral blood flow in conscious humans and its potential to predict future ischemic events. J Am Coll Cardiol, 1995,25:1522-1528.
  • 10[10]Nakamura M, Tsunoda T, Wakatsuki T, et al. Safety and feasibility of continuous monitoring of coronary flow velocity in acute myocardial infarction by Doppler guide wire. Am Heart J, 1996,132:567-571.

共引文献4

同被引文献2

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部