摘要
目的筛选角茴香发挥保肝、镇痛、抗炎作用的有效部位。方法用系统溶剂分离法将角茴香分离成极性不同的组分,通过角茴香不同组分对硫代乙酰胺致肝损伤的保护作用、角茴香不同组分对热板法引起小鼠疼痛的影响以及角茴香不同组分对二甲苯所至小鼠耳肿胀的影响,筛选角茴香发挥保肝、镇痛以及抗炎作用的有效部位。结果角茴香正丁醇提取部位为角茴香发挥保肝作用的物质基础,氯仿提取物为角茴香发挥镇痛抗炎作用的有效部位。
Objective To select the effective parts in Fruetus Illcii Veil on protecting liver, releasing pain and anti - inflammation. Method Divided Fmetus Illieii Veri into groups according to different polarities with system solution exclusion. Selected the effective parts in Fruetus mieii Veri on protecting liver, releasing pain and anti - inflammation by the protective effect of different groups on liver injury due to thioacetamide, effect of different groups on mice＇ s pain because of hot plate and effect of different groups on mice＇s ear swelling owing to dimethyl benzene. Result The parts for extracting n- butanol in Fructus Illicii Veri was substances protecting the liver, while chloroform extract was the effective parts fot releasing pain and anti- inflammation.
出处
《陕西中医学院学报》
2006年第2期58-60,共3页
Journal of Shaanxi College of Traditional Chinese Medicine
基金
陕西省中医管理局资助项目1(2005058)
关键词
角茴香
活性部位
药理研究
Fructus Illicii Veri
active parts
pharmacological study
