摘要
目的揭示广东省护理人员职业接触化疗药物产生的不良反应现状及特征,探讨职业接触化疗药物各环节与产生不良反应之间的关系。方法对广东省的一甲、二甲、三甲各10所医院的护士进行回顾性调查分析,共有993名护士接受调查,除去删失数据,其中接触组护士717名及对照组213名进入分析。接触组为平时工作有接触化疗药物经历的护士,对照组为绝对未接触化疗药物的护士。结果接触组护士产生不良反应均显著高于对照组(P<0.001);在此基础上进一步对接触组护士产生不良反应的危险因素进行Logistic回归分析,经调整混杂因素后,处理溢出、输液次数是产生不良反应的危险因素(P<0.05)。结论广东省护理人员职业接触化疗药物导致急性不良反应的危险性增加。研究发现,处理溢出、输液次数、输液种类是产生不良反应的危险因素。
Objective To explore the current situation and feature of adverse effects in nurses with occupational exposure to chemotherapeutic drugs in Guangdong Province and investigate the relationship between adverse effects and each steps at handling chemotherapeutic drugs by nurses. Methods A restrospective investigation was carried out among 30 hospitals in Guangdong Province, 717 nurses who had the experience of handling the chemotherapeutic drugs and 213 nurses who had never been exposed to the same drugs involving the study. Results The rate of adverse effects among nurses exposed to the chemotherapeutic drugs is significantly higher than that of the nurses without exposure （P〈0.001）, Logistic repression analysis after adjustment of mixed effects indicated that frequent performances and frequently dealing with overflow were risk factors for adverse effects （P〈0.05）. Conclusion The risk of adverse reaction in nurses of Guangdong Province with exposure to chemotherapeutic drugs is going up. Frequent performances and frequently dealing with overflow are risk factors.
出处
《护理学报》
2006年第3期83-85,共3页
Journal of Nursing（China）
关键词
广东省
化疗药物
职业暴露
不良反应
Guangdong Province
chemotherapeutic drugs
occupational exposure
adverse effects
