摘要
为探讨胸腺激素耐受的最高温度，将胸腺因子Ｄ、胸腺素和胸腺肽加热至１２１℃、１２５℃、１３０℃，直至１９０℃１５ｍｉｎ。结果：加热１４０℃以下１５ｍｉｎ，其色泽、澄明度、紫外吸收峰、旋光度、ＰＨ值、蛋白质含量、相对比移值和活性玫瑰花形成率，与未加热样品比较，均无明显变化；加热至１５０℃以上，上述指标除紫外吸收峰外，余均显著改变。结果表明，胸腺因子Ｄ、胸腺素和胸腺肽能耐受１４０℃１５ｍｉｎ。
The influence of heat on physicochemical properties and bioactivities of thymus hormone was observed when the thymus factor D (TFD),thymosin (TM) and thymopeptide (TP) were heated to 121,125,130,140,150,160,170,180,190 degrees centigrade for 15 min. When the temperature under 140 degrees centigrade, the color, clarity, ultraviolet absorb peak,optical rotation,PH valueprotien content,Rf value and active rosette forming rate were not significantly change compared with those of TH before heat.But when the temperature over 150 degrees centigrade,these markers as mentioned above,except ultraviolet absorb peak were all significantly changed.These results suggest that the TFD,TM,and TP resisted 140 degrees centigrade 15 miniutes.
出处
《微生物学免疫学进展》
1996年第2期49-52,共4页
Progress In Microbiology and Immunology
基金
福建省自然科学基金
关键词
胸腺激素
理化性质
温度
生物活性
生物制品
Thymus hormone Thermostability Activity Physicochemical properties
