摘要
目的:观察强肝解毒汤联合干扰素α-1b治疗慢性乙肝的疗效及安全性。方法:临床选取慢性乙肝病例治疗组给强肝解毒汤联合干扰素α-1b,对照组给甘利欣胶囊联合干扰素α-1b,观察TBIL、ALT的复常律及HBsAg、HBeAg、HBV-DNA的阴转情况及其两组的不良反应。结果:治疗组在这些指标上明显优于对照组,差异具有显著性意义,两组均无太大的不良反应。结论:强肝解毒汤联合干扰素α-1b对恢复慢性乙肝患者肝功能,抑制病毒复制,抗肝纤维化有较好作用。
Objective: To obese the effect and safety of qianggan jiedu decoction plus interferon-alpha(α) - 1b treating chronic hapetitis B. Methods: Treatment group was treated with qinggan jiedu decoction phks interferon-alpha(α) - 1b, and control group was treated with ganlixin capsules plus interferon-alpha(α) - 1b. To observe the recovery rate of TBIL, ALT and the changeover rate of HBsAg, HBeAg, HBV- DNA and the side effects of the two groups. Results: Treatment group was better than control group, and there was markedly difference. In the two groups there were not serious side effects. Conclusion: Qianggan jiedu decoction plus interreran-alpha(α) - 1b had good effects of recovering liver function, inhibiting virus and resisting hepatic fibrosis.
出处
《河南中医学院学报》
2006年第2期48-49,共2页
Journal of Henan University of Chinese Medicine
关键词
慢性乙型肝炎
强肝解毒汤
干扰素α—1b
甘利欣胶囊
chronic hepatitis B
qianggan jiedu decoction
interferon-alpha(α) - 1b
ganlixin capsules