摘要
目的探讨联合检测抗环瓜氨酸多肽(CCP),抗角蛋白(AKA)和抗RA33这三种自身免疫性抗体对类风湿关节炎(RA)早期诊断的意义。方法对250例RA患者和198例其他自身免疫病患者进行抗CCP,AKA,RA33抗体的测定。以50名健康体检患者作为正常对照。结果RA患者的抗CCP,AKA和RA33抗体的阳性率比其他自身免疫病患者和健康体检患者高,有显著性差异;抗CCP的敏感性比抗AKA和抗RA33高,有显著性差异。三种抗体联合检测比两种抗体两两联合检测特异性好有显著性差异。结论抗CCP,AKA,RA33抗体联合检测对RA的早期诊断有非常重要的价值。
Objective To discuss the diagnostic value of anti-CCP , anti-AKA and anti-RA33 for the early rheumatoid arthritis （RA） . Methods Testing anti-CCP , anti-AKA and anti-RA33 in 250 cases of RA patients and 198 cases of Undifferentiated inflammatory arthritis （UIA） patients , 50 cases of healthy individuals. Results In the RA , the positive rate of anti-CCP , anti-AKA and anti-RA33 were higher than UIA and healthy individuals, The sensitivities of anti-CCP is higher than anti-AKA and anti-RA33. The specialties rate of combine detection three antibodies is higher than each two antibodies. Conclusion Combined detection of anti-CCP , anti-AKA and anti-RA33 are helpful for diagnosis of the early RA .
出处
《现代医院》
2006年第3期60-61,共2页
Modern Hospitals
