摘要
目的对比研究血管回声跟踪(echo-tracking,ET)技术和M型超声评价动脉僵硬度的价值。方法52只新西兰兔随机分为对照组1、高胆固醇血症组、对照组2和动脉粥样硬化组,普通或高胆固醇饲养建立相应的模型。导管测量兔股动脉血压。在基础点和模型建立后,两位医师用ET技术和M型超声检测兔腹主动脉僵硬度各2次。结果动脉粥样硬化组兔胸腹主动脉均有脂质斑块形成,斑块下弹力纤维板疏松、断裂。与M型超声比较,ET技术检测的动脉僵硬度指标[弹性系数(Eρ)、硬度指数(β)和顺应性(AC)]变异系数较小,Eρ和β敏感,2种方法测量的AC均不敏感;ET技术取血管短轴切面检测Eρ、β和AC的稳定性与常规取长轴切面相似,但敏感度较低。结论ET技术评价动脉僵硬度较传统M型超声稳定、敏感,以取血管长轴检查为宜。僵硬度指标Eρ和β较敏感,AC敏感度低。
Objective To study the worth of echo-tracking and M-echo in evaluating artery stiffness comparatively. Methods Fifty two rabbits were divided into 4 groups randomly： control group 1, hypereholesterinemia group, control group 2,and artheroselerosis group, there were 13 rabbits in each group. The rabbits were bred with normal or 2 % cholesterol animal feeds according to their groups. The femoral artery blood pressure were measured with catheter, Artery stiffness of abdomen aorta of every rabbit was evaluated by echotracking and M-echo at the baseline and the end of the study by 2 doctors,and each doctor did twice. Results All the rabbits of artheroselerosis group had lipid plaques in the thorax and abdomen aortas,and the interior elastic fibers board under the plagues were disrupted, Echo-tracking was more stable and sensitive than M-echo in evaluating artery stiffness, pressure-strain elastic modulus （Eρ） and stiffness index（β） were sensitive stiffness indexes,but arterial eomplianee（AC） was not. The indexes of artery stiffness evaluated by echo-tracking with short view of the artery were stable too, but not sensitive compared with long view. Eρ was relative to diastolic diameter of artery and HDL-C positively（ P 〈0.05） ,but β and AC were not. Eρ,β and AC were not relative to systolic blood pressure, diastolic blood pressure, heart rate, systolic diameter of artery, blood glucose, TG, CH and HDL-C（ P 〉0.05）, Conclusions Echo-tracking is more stable and sensitive than M-echo in evaluation of artery stiffness,long view of the artery should be applied in the evaluation of artery stiffness with the technique of echotracking. Eρ and β were sensitive artery stiffness indexes,but AC was not.
出处
《中华超声影像学杂志》
CSCD
2006年第3期223-226,共4页
Chinese Journal of Ultrasonography
关键词
超声检查
动脉硬化
高胆固醇血症
Ultrasonography
Artheriosclerosis
Hypercholesterdemia
