摘要
本研究从载体系统和靶向制剂两方面,回顾了最近有关药物防治后囊混浊的研究成果。这其中包括有抗体介导的靶向药物、脂质体、纳米毫微粒及药物载体植入剂系统。文章介绍了它们各自在提高利用度、延长有效作用时间、增加靶向性方面的特点以及在体外和临床上的应用效果。
This review summarizes recent work directed towards the treatment of posterior capsular opacification (PCO) with drugs, whether through mofe specific anti-lens agents or through methods of delivery. These areas indude antibody-targeted therapies, liposome, nanoparticles, and drug-detivery systems, based on the utilization of enhanced availability and retetion effect and specific targeting. The ability to treat PCO in vitro and in clinical trials is also discussed.
出处
《眼视光学杂志》
2006年第1期57-59,共3页
Chinese Journal of Optometry & Ophthalmology
关键词
后囊混浊/药物治疗
缓释系统
靶向治疗
综述文献
posterior capsuler opecification/drug therapy
drag delivery system
target therapy
review articles