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遗传性心律失常基因研究近况 被引量：6

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摘要 遗传性心律失常由细胞离子通道、细胞骨架蛋白、细胞间连接蛋白等基因突变导致细胞电生理功能异常引起,通过归纳基因特征性临床特点,可对心律失常的易感性和遗传性进行评估,作出早期诊断,并采取相应的防范措施。特异性基础治疗还处于动物实验阶段,其结果令人鼓舞。致病基因所致的临床表现受多种因素的影响,其与临床表现的关系复杂,还受基因多态性以及修饰因子的影响。心律失常基因研究领域还存在很多复杂问题有待解决。
作者 马克娟 浦介麟
机构地区 中国协和医科大学阜外心血管病医院心律失常诊治中心
出处 《中国心脏起搏与心电生理杂志》 2006年第1期4-7,共4页 Chinese Journal of Cardiac Pacing and Electrophysiology
关键词 心血管病学 心律失常 综述 离子通道 基因治疗
分类号 R541.7 [医药卫生—心血管疾病] R331.38 [医药卫生—人体生理学]
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参考文献26

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二级参考文献12

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共引文献16

同被引文献64

引证文献6

二级引证文献15

中国心脏起搏与心电生理杂志
2006年 第1期

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