摘要
目的探讨胃肠道间质瘤(GIST)的临床表现、组织学和免疫组化的特点及治疗方法。方法回顾总结2000年1月至2005年6月收治的32例GIST患者的临床和组织学资料,应用免疫组化方法进行分析研究。结果GIST主要发生在胃(56.25%)和小肠(31.25%),结直肠少见(6.25%)。CD117阳性表达率为93.75%,CD34阳性表达率为76.8%。结论GIST是胃肠道最常见的间质性肿瘤,CD117和CD34标记阳性是确诊GIST最有价值的诊断依据,手术是主要的治疗手段。
Objective To investigate the speciality of clinical features,histology and immunohiatochemical of GIST,and to explore the therapy of GIST. Methods The clinical datas and immunohistochemical of 32 patients with gastrointestinal stromal tumor were reviewed. Results Of them, 18 tumorus originated in the stomach, 10 cases were in small bowel;2 cases were originated in the colorectal. Positive of CD117 and CD34 in the GIST were 93. 75 % and 76.8 %. Conclusions GIST is the most common tumor in gastroimcsrinal mesenchymal rumor, CD117 and CD34 is a senitive marker for GIST, which plays an important role in the differential diagnosis of gastrointestinal mesenchymal rumor. Surgical operation is the main method to manage GIST.
出处
《中国基层医药》
CAS
2006年第1期32-33,共2页
Chinese Journal of Primary Medicine and Pharmacy
