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蛋白质类药物微粒制剂制备方法研究进展 被引量:8

Research advances in the preparation of the protein loaded microparticles
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摘要 综述了近年来有关制备蛋白质类药物微粒制剂的研究进展,包括溶剂挥发法、溶剂-非溶剂法、吸附法、喷雾干燥法、核芯包衣法制备微球和海藻酸钠/壳聚糖微球、脂质体微球、原位微球、水凝胶锚定脂囊泡系统的方法。
出处 《中国生化药物杂志》 CAS CSCD 2006年第1期52-55,共4页 Chinese Journal of Biochemical Pharmaceutics
关键词 蛋白质 微球 制备
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参考文献20

  • 1Bittner B,Witt C,Mader K,et al.Degradation and protein release properties of microspheres prepared from biodegradable poly(lactide-co-glycolide)and ABA triblock copolymers:influence of buffer media on polymer erosion and bovine serum albumin release[J].J Controlled Release,1999,60(2,3):297-309.
  • 2Moynihan JS,Blair J,Coombes A,et al.Enhanced immunogenicity of a hepatitis B virus peptide vaccine using oligosaccharide ester derivative microparticles[J].Vaccine,2002,20(13):1870-1876.
  • 3Pistel KF,Breitenbach A,Zange-Volland R,et al.Brush-like branched biodegradable polyesters,part III Protein release from microspheres of poly(vinyl alcohol)-graft-poly(D,L-lactic-co-glycolic acid)[J].J Controlled Release,2001,73(1):7-20.
  • 4Chia HH,Yang YY,Chung TS,et al.Auto-catalyzed poly(ortho ester)microspheres:a study of their erosion and drug release mechanism[J].J Controlled Release,2001,75(1,2):11-25.
  • 5Bezemer JM,Grijpma DW,Dijkstra PJ,et al.Control of protein delivery from amphiphilic poly(ether ester)multiblock copolymers by varying their water content using emulsification techniques[J].J Controlled Release,2000,66(2,3):307-320.
  • 6Yang YY,Chung TS,Bai XL,et al.Effect of preparation conditions on morphology and release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion method[J].Chem Eng Sci,2000,55(12):2223-2236.
  • 7Cleland JL,Lim A,Barron L,et al.Development of a single-shot subunit vaccine for HIV-1:Part 4.Optimizing microencapsulation and pulsatile release of MN rgp120 from biodegradable microspheres[J].J Controlled Release,1997,47(2):135-150.
  • 8Li XH,Deng XM,Yuan ML,et al.Investigation on process parameters involved in preparation of poly-DL-lactide-poly(ethylene glycol)microspheres containing Leptospira Interrogans antigens[J].Int J Pharm,1999,178(2):245-255.
  • 9Sturesson C,Carlfors J.Incorporation of protein in PLG-microspheres with retention of bioactivity[J].J Controlled Release,2000,67(2,3):171-178.
  • 10Sanchez A,Villamayor B,Guo Y,et al.Formulation strategies for the stabilization of tetanus toxoid in poly(lactide-co-glycolide)microspheres[J].Int J Pharm,1999,185(2):255-266.

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