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注射用水溶性维生素在重型颅脑外伤患者合理性应用的评价 被引量:1

The Evaluation of the Injection of Water Soluble Vitamins in the Therapy of Intensive Craniocerebral Trauma
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摘要 探讨注射用水溶性维生素(凯潍)在重型颅脑外伤患者治疗中的应用价值。将90例重型颅脑外伤患者随机分为对照组和治疗组,对照组单独用全肠外营养(TPN),治疗组在TPN的基础上加用注射水溶性维生素1瓶,1次/天,连用7 d。结果:治疗组给药7天后4 h内尿负荷试验中维生素B1,维生素B2,维生素C排出量明显高于治疗后对照组(P<0.05);治疗后7天,检测血清IgGI、gA、IgM水平及血红蛋白(Hb)含量,治疗组与治疗前相比明显上升(P<0.05),而对照组与治疗前相比无显著变化(P>0.05);GCS评分方面,治疗组与治疗前相比明显上升(P<0.05),而对照组与治疗前相比无显著变化(P>0.05)。结论:注射用水溶性维生素(凯潍)在重型颅脑外伤患者营养支持中有非常重要的地位,作用不可替代。 To study the availability of the injection of water soluble vitamin in the therapy of intensive craniocerebral trauma. Go patients were randomly devided into control group and therapy group. Control group received Total Parenteral Nutrition(TPN). Therapy group not only received TPN but also received a bottle of the injection of water soluble vitamin once a day for 7 days. The results indicated that in urinary load test the contents of Vitamin B1, Vitamin B2, Vitamin C of therapy group were significantly higher than those of control group in 4h after 7 days' therapy , the contents of IgG, IgA, IgM and Hb of therapy group were significantly higher than those before therapy, and the rank of GCS of therapy group was significantly higher than that before therapy(P〈0. 05). However, no significant differences were found in the contents of IgG, IgA, IgM ,Hb and the rank of GCS of Control group be tween before therapy and after therapy. From the test, it can be concluded that the injection of water soluble vitamin is very important in the nutrition therapy of intensive craniocerebral trauma.
出处 《药物生物技术》 CAS CSCD 2006年第1期55-58,共4页 Pharmaceutical Biotechnology
关键词 重型颅脑外伤 营养支持 水溶性维生素 Intensive craniocerebral trauma, Nutrition therapy, Soluble vitamin.
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